ACVR2B
activin A receptor, type IIB
동의어:
ACTRIIB, ActR-IIB, HTX4
종:
Human ACVR2B (93), Mouse Acvr2b (11481), Rat Acvr2b (25366), Horse ACVR2B (100053588), domestic cat ACVR2B (101086087), dog ACVR2B (485590), naked mole-rat Acvr2b (101711703), Zebrafish acvr2b (30457), chicken ACVR2B (374213), domestic guinea pig Acvr2b (100722791) ...더
UniProtKB ID:
Clone ID:
- Human(93) Summary: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
- Mouse(11481) activin receptor IIB
- Rat(25366) activin A receptor, type IIB
- Horse(100053588) activin A receptor, type IIB
- domestic cat(101086087) activin A receptor, type IIB
- dog(485590) activin A receptor, type IIB
- naked mole-rat(101711703) activin A receptor, type IIB
- Zebrafish(30457) activin receptor IIb
- chicken(374213) activin A receptor, type IIB
- domestic guinea pig(100722791) activin A receptor, type IIB
- sheep(443156) activin A receptor, type IIB
- cow(282131) activin A receptor, type IIB
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
제품 번호
설명
종
Antibodies
제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-ACVR2B antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
western blot
Anti ACVR2B Antibody, clone 23GB620, Rabbit Monoclonal, clone 23GB620, recombinant rabbit monoclonal, expressed in HEK293 cells,
종별 반응성
human, rat
응용분야
immunofluorescence
western blot
western blot
Anti-Activin Receptor IIB antibody produced in goat, affinity isolated antibody,
종별 반응성
human
응용분야
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ACVR2B antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, rat, sheep
응용분야
western blot
Anti-ACVR2B (C-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
western blot