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Merck

APP

amyloid beta (A4) precursor protein

동의어:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
종:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
UniProtKB ID:
P05067, B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438
Clone ID:
  • Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11820) amyloid beta (A4) precursor protein
  • Rat(54226) amyloid beta (A4) precursor protein
  • fruit fly(39399) approximated
  • chicken(374198) amyloid beta (A4) precursor protein
  • dog(403407) amyloid beta (A4) precursor protein
  • domestic cat(101085564) amyloid beta (A4) precursor protein
  • cow(280722) amyloid beta (A4) precursor protein
  • sheep(101111593) amyloid beta (A4) precursor protein
  • domestic guinea pig(100715302) amyloid beta (A4) precursor protein
  • naked mole-rat(101724743) amyloid beta (A4) precursor protein

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ELISA

제품 번호
설명
종
RAB0530
Human APP / Amyloid Beta A4 Protein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
종
human
EZBRAIN-SET
Human Amyloid β40 and Amyloid β42 Brain ELISA, ,
종
human
EZHS42
High Sensitivity Human Amyloid β42 ELISA, ,
종
human
EZHS40
High Sensitivity Human Amyloid β40 ELISA, ,
종
human
EZBRAIN42
Human Amyloid β42 Brain ELISA, ,
종
human

Small Molecule - Antagonist

제품 번호
설명
종
B9934
BTA-1, ≥98% (HPLC), solid,
종
human
C7727
Curcumin, ≥94% (curcuminoid content), ≥80% (Curcumin),
종
human
C1386
Curcumin, from Curcuma longa (Turmeric), powder,
종
human
F8514
Flurbiprofen, cyclooxygenase inhibitor,
종
human, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
AB5078P
Anti-Beta-Amyloid 1-42 Antibody, Chemicon®, from rabbit,
종별 반응성
chicken, human, mouse
응용분야
ELISA
immunohistochemistry
western blot
MABN639
Anti-Amyloid βA4, clone 1E8 (Amino Terminus) Antibody, clone 1E8, 1 mg/mL, from mouse,
종별 반응성
human
응용분야
immunohistochemistry
immunoprecipitation (IP)
western blot
MABN10
Anti-Amyloid β Antibody, clone W0-2, clone WO2, from mouse,
종별 반응성
human, mouse
응용분야
ELISA
immunohistochemistry
western blot
MABN254
Anti-amyloid beta peptide (MOAB-2), pan Antibody, clone 6C3, clone 6C3, from mouse,
종별 반응성
human
응용분야
dot blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
MABN13
Anti-Amyloid β42 Antibody, clone G2-13, clone G2-13, from mouse,
종별 반응성
human, mouse
응용분야
ELISA
immunohistochemistry
western blot

Proteins

제품 번호
설명
종
AG916
β Amyloid 1-42, aβ, scrambled, TFA, recombinant E. coli, ,
종
human
AG970
β Amyloid 1-42, aβ, ultra pure, NaOH, recombinant human, ,
종
human
03-0146-00
SMC® Amyloid Beta 42 High Sensitivity Immunoassay Kit, ,
종
A2201
Amyloid β-Protein Fragment 35-25, ≥95% (HPLC),
종
human
S4316
Amyloid Precursor Protein β, Secreted human, recombinant, expressed in E. coli (N-terminal histidine tagged), solution,
종
human

esiRNA

제품 번호
설명
종
EHU085701
MISSION® esiRNA, targeting human APP,
종
human
EMU012021
MISSION® esiRNA, targeting mouse App,
종
mouse