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Merck

APP

amyloid beta (A4) precursor protein

동의어:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
종:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
UniProtKB ID:
P05067, B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438
Clone ID:
  • Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11820) amyloid beta (A4) precursor protein
  • Rat(54226) amyloid beta (A4) precursor protein
  • fruit fly(39399) approximated
  • chicken(374198) amyloid beta (A4) precursor protein
  • dog(403407) amyloid beta (A4) precursor protein
  • domestic cat(101085564) amyloid beta (A4) precursor protein
  • cow(280722) amyloid beta (A4) precursor protein
  • sheep(101111593) amyloid beta (A4) precursor protein
  • domestic guinea pig(100715302) amyloid beta (A4) precursor protein
  • naked mole-rat(101724743) amyloid beta (A4) precursor protein

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ELISA

제품 번호
설명
종
EZBRAIN-SET
Human Amyloid β40 and Amyloid β42 Brain ELISA, ,
종
human
RAB0530
Human APP / Amyloid Beta A4 Protein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
종
human
EZHS40
High Sensitivity Human Amyloid β40 ELISA, ,
종
human
EZBRAIN42
Human Amyloid β42 Brain ELISA, ,
종
human
EZHS42
High Sensitivity Human Amyloid β42 ELISA, ,
종
human

Small Molecule - Antagonist

제품 번호
설명
종
B9934
BTA-1, ≥98% (HPLC), solid,
종
human
C7727
Curcumin, ≥94% (curcuminoid content), ≥80% (Curcumin),
종
human
C1386
Curcumin, from Curcuma longa (Turmeric), powder,
종
human
F8514
Flurbiprofen, cyclooxygenase inhibitor,
종
human, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
A3981
Anti-β-Amyloid antibody, Mouse monoclonal, clone BAM-10, purified from hybridoma cell culture,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
western blot
A8326
Anti-β-Amyloid Protein (1-40) antibody produced in rabbit, whole antiserum,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
A5213
Anti-β-Amyloid antibody, Mouse monoclonal, clone BAM-10, ascites fluid,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
SAB2501664
Anti-App (N-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
mouse, rat
응용분야
ELISA
western blot
A8978
Anti-β-Amyloid (13-28) antibody, Mouse monoclonal, clone BAM90.1, purified from hybridoma cell culture,
종별 반응성
human
응용분야
enzyme immunoassay
immunohistochemistry
immunoprecipitation (IP)
western blot

Proteins

제품 번호
설명
종
A6933
Acetyl-Amyloid β-Protein Fragment 15-20 Amide, ≥97% (HPLC), powder,
종
human
A2201
Amyloid β-Protein Fragment 35-25, ≥95% (HPLC),
종
human
A5080
Amyloid β-Protein Fragment 22-35, ≥95% (HPLC),
종
human
A0189
Amyloid β Protein Fragment 1-38, ≥95% (HPLC), powder,
종
human
A1972
[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt, ≥95% (HPLC), solid,
종
human

esiRNA

제품 번호
설명
종
EHU085701
MISSION® esiRNA, targeting human APP,
종
human
EMU012021
MISSION® esiRNA, targeting mouse App,
종
mouse