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Merck

BAD

BCL2-associated agonist of cell death

동의어:
BBC2, BCL2L8
:
UniProtKB ID:
Clone ID:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

Custom & Knockdown Gene Products

Small Molecule - Antagonist

제품 번호
설명
2,3-Dihydroxynaphthalene, ≥98.0% (HPLC),
human
4-Biphenylacetic acid, 98%,
human
Biphenyl-4-carboxylic acid, 95%,
human
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
종별 반응성
bovine, canine, human, mouse, rat
응용분야
immunoprecipitation (IP)
inhibition assay

western blot
Anti-Phospho- Bad (Ser75) Antibody, from rabbit,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-Bad antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-BAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-Phospho-Bad-S155 antibody produced in rabbit, ,
종별 반응성
human
응용분야
western blot

Proteins

제품 번호
설명
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human BAD,
human