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Merck

BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

동의어:
HUCEP-13, UCHL2
:
UniProtKB ID:
Clone ID:
  • Human(8314) Summary: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
  • Mouse(104416) Brca1 associated protein 1
  • Rat(306257) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Thale Cress(825291) BON association protein 1
  • domestic cat(101092671) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • domestic guinea pig(100731081) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Zebrafish(558885) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • chicken(415944) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • naked mole-rat(101703932) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • dog(484737) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • cow(100124510) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • Horse(100051934) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • sheep(101111666) BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-BAP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Rabbit anti-BAP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
종별 반응성
human
응용분야
immunoprecipitation (IP)
western blot
Anti-BAP1 Antibody, clone 3C11, clone 3C11, from mouse,
종별 반응성
human
응용분야
immunoprecipitation (IP)
western blot
Anti-BAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-BAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human BAP1,
human
MISSION® esiRNA, targeting mouse Bap1,
mouse