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Merck

BIN1

bridging integrator 1

동의어:
AMPH2, AMPHL, SH3P9
:
UniProtKB ID:
Clone ID:
  • Human(274) Summary: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011]
  • Mouse(30948) bridging integrator 1
  • Rat(117028) bridging integrator 1
  • Zebrafish(447863) bridging integrator 1
  • chicken(424228) bridging integrator 1
  • domestic guinea pig(100722858) bridging integrator 1
  • dog(483870) bridging integrator 1
  • sheep(101119119) bridging integrator 1
  • naked mole-rat(101723039) bridging integrator 1
  • fruit fly(41965) Bicoid interacting protein 1
  • domestic cat(101097908) bridging integrator 1
  • Horse(100052213) bridging integrator 1
  • cow(614576) bridging integrator 1

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-BIN1 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-BIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-BIN1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-Bin1 Antibody, clone 99D, clone 99D, Upstate®, from mouse,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Bin1 antibody produced in mouse, clone 99D, ascites fluid,
종별 반응성
avian, human, mouse, rabbit, rat
응용분야
ELISA
flow cytometry

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human BIN1,
human
MISSION® esiRNA, targeting mouse Bin1,
mouse