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Merck

BRD2

bromodomain containing 2

동의어:
D6S113E, FSH, FSRG1, NAT, RING3, RNF3
:
UniProtKB ID:
Clone ID:
  • Human(6046) Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(14312) bromodomain containing 2
  • Rat(294276) bromodomain containing 2
  • domestic guinea pig(100734555) bromodomain containing 2
  • cow(505358) bromodomain containing 2
  • Domestic Rabbit(100343906) bromodomain containing 2
  • domestic cat(101084362) bromodomain containing 2
  • sheep(101110276) bromodomain containing 2
  • chicken(417049) bromodomain containing 2
  • dog(474868) bromodomain containing 2
  • naked mole-rat(101699681) bromodomain containing 2

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-BRD2 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Rabbit anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
종별 반응성
human, mouse
응용분야
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti Bromodomain containing 2 Antibody, clone 23GB1645, Rabbit Monoclonal, clone 23GB1645, recombinant rabbit monoclonal, expressed in HEK293 cells,
종별 반응성
human
응용분야
flow cytometry
immunofluorescence

western blot
Anti-BRD2 Antibody, from rabbit, purified by affinity chromatography,
종별 반응성
human, rat
응용분야
immunohistochemistry
western blot
Anti-BRD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
OTX015, ≥98% (HPLC),
human
I-BET762, ≥98% (HPLC),
human

Proteins

제품 번호
설명
BRD2 (339-459) GST tag human, recombinant, expressed in E. coli, ≥86% (SDS-PAGE),
human
BRD2 (65-187) GST tag human, recombinant, expressed in E. coli, ≥81% (SDS-PAGE),
human
BRD2 (65-187) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
human
BRD2, BD1, BD2 (65-459) GST tag human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Brd2,
mouse
MISSION® esiRNA, targeting human BRD2,
human