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Merck

CDK2

cyclin-dependent kinase 2

동의어:
p33(CDK2)
:
UniProtKB ID:
Clone ID:
  • Human(1017) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(12566) cyclin-dependent kinase 2
  • Rat(362817) cyclin dependent kinase 2
  • domestic guinea pig(100714324) cyclin-dependent kinase 2
  • Zebrafish(406715) cyclin-dependent kinase 2
  • chicken(100529062) cyclin-dependent kinase 2
  • naked mole-rat(101725353) cyclin-dependent kinase 2
  • dog(606931) cyclin-dependent kinase 2
  • domestic cat(101093368) cyclin-dependent kinase 2
  • sheep(100216433) cyclin-dependent kinase 2
  • Domestic Rabbit(100134865) cyclin-dependent kinase 2
  • cow(519217) cyclin-dependent kinase 2
  • Goat(100860751) cyclin-dependent kinase 2

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CDK2 antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
bovine, goat, human, mouse, rabbit, rat, sheep
응용분야
immunohistochemistry
western blot
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-phospho-CDK1/CDC2 (pThr14) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

western blot
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-Phospho-CDK2-Y15 antibody produced in rabbit, ,
종별 반응성
human
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
Piceatannol, powder,
human
Tyrphostin 23, ≥98%,
human
Tyrphostin 51, ≥98%,
human
6-O-Methylguanine, 97%,
human
Bisindolylmaleimide IV, ≥98% (TLC), solid,
human, rat

Proteins

제품 번호
설명
Cdk2/Cyclin E Protein, active, 10 µg, Active complex of recombinant full length human Cdk2 containing a C-terminal His6-tag & recombinant full-length human Cyclin E containing an N-terminal GST-tag. For use in Kinase Assays.,
human
Cdk1/cyclin B Protein, active, 10 µg, Active, C-terminal His6-tagged human full length Cdk1 & N-terminal GST-tagged human full length Cyclin B, for use in Kinase Assays.,
human
CDK2/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human
p27 Protein complex, activated, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CDK2,
human
MISSION® esiRNA, targeting mouse Cdk2,
mouse