CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
동의어:
CDK4I, INK4B, MTS2, P15, TP15, p15INK4b
종:
Human CDKN2B (1030), Mouse Cdkn2b (12579), Rat Cdkn2b (25164), Horse CDKN2B (100034122), dog CDKN2B (481563), chicken CDKN2B (395076), domestic guinea pig Cdkn2b (100732246), sheep CDKN2B (101107164), cow CDKN2B (527124), domestic cat CDKN2B (101087014)
UniProtKB ID:
Clone ID:
- Human(1030) Summary: This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
- Mouse(12579) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- Rat(25164) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- Horse(100034122) cyclin-dependent kinase 2B inhibitor
- dog(481563) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- chicken(395076) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- domestic guinea pig(100732246) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- sheep(101107164) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- cow(527124) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- domestic cat(101087014) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-CDKN2B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-p15 INK antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Cdkn2B Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
Anti-INK4b (p15) Antibody, clone GF10 (10C7A6), culture supernatant, clone GF10 (10C7A6), from mouse,
종별 반응성
human
응용분야
western blot
Anti-CDKN2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Small Molecule - Inhibitor
Kits
제품 번호
설명
종
CpG WIZ™ p15 -Methylation specific PCR assay, The CpG WIZ p15 Amplification Kit is used for determining the methylation status of the p15 promoter by methylation-specific PCR (MSP).,
종
human
esiRNA
제품 번호
설명
종