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Merck

CHN2

chimerin 2

동의어:
ARHGAP3, BCH, CHN2-3, RHOGAP3
:
UniProtKB ID:
Clone ID:
  • Human(1124) Summary: This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(69993) chimerin (chimaerin) 2
  • Rat(84031) chimerin 2
  • domestic cat(101093762) chimerin 2
  • Domestic Rabbit(100344407) chimerin 2
  • dog(475267) chimerin 2
  • Zebrafish(570999) chimerin (chimaerin) 2
  • domestic guinea pig(100723720) chimerin 2
  • naked mole-rat(101701673) chimerin 2
  • chicken(428437) chimerin (chimaerin) 2
  • cow(507285) chimerin (chimaerin) 2
  • sheep(101103716) chimerin 2

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CHN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-CHN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CHN2,
human
MISSION® esiRNA, targeting human CHN2 (2),
human
MISSION® esiRNA, targeting mouse Chn2,
mouse