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Merck

MAP2K7

mitogen-activated protein kinase kinase 7

동의어:
Jnkk2, MAPKK7, MKK7, PRKMK7, SAPKK-4, SAPKK4
:
UniProtKB ID:
Clone ID:
  • Human(5609) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008]
  • Mouse(26400) mitogen-activated protein kinase kinase 7
  • Rat(363855) mitogen activated protein kinase kinase 7
  • dog(485004) mitogen-activated protein kinase kinase 7
  • Zebrafish(560913) mitogen-activated protein kinase kinase 7
  • domestic guinea pig(100731057) mitogen-activated protein kinase kinase 7
  • domestic cat(101095157) mitogen-activated protein kinase kinase 7
  • sheep(100302082) mitogen-activated protein kinase kinase 7
  • cow(787278) mitogen-activated protein kinase kinase 7
  • naked mole-rat(101710666) mitogen-activated protein kinase kinase 7

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-MAP2K7, (N-terminal) antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence

immunohistochemistry

proximity ligation assay

western blot
Monoclonal Anti-MAP2K7 antibody produced in mouse, clone 6A4, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-MEK7 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-phospho-MAP2K7 (pThr275) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
western blot
Anti-MAP2K7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry

Small Molecule - Inhibitor

제품 번호
설명
PD 98,059, solid,
human

Proteins

제품 번호
설명
MKK7β1 Protein, inactive, 50 g, Unactive, N-terminal GST-tagged, recombinant, human MKK7β1 amino acids 2-end, for use in Kinase Assays.,
human
MKK7β1 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human MKK7β1, amino acids 2-end. For use in Kinase Assays.,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human MAP2K7,
human
MISSION® esiRNA, targeting mouse Map2k7,
mouse