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Merck

MMP14

matrix metallopeptidase 14 (membrane-inserted)

동의어:
MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1
:
UniProtKB ID:
Clone ID:
  • Human(4323) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
  • Mouse(17387) matrix metallopeptidase 14 (membrane-inserted)
  • Rat(81707) matrix metallopeptidase 14 (membrane-inserted)
  • naked mole-rat(101723795) matrix metallopeptidase 14 (membrane-inserted)
  • sheep(443116) matrix metallopeptidase 14 (membrane-inserted)
  • cow(281915) matrix metallopeptidase 14 (membrane-inserted)
  • Domestic Rabbit(100009598) matrix metallopeptidase 14 (membrane-inserted)
  • domestic guinea pig(100732039) matrix metallopeptidase 14 (membrane-inserted)
  • dog(403823) matrix metallopeptidase 14 (membrane-inserted)
  • Horse(100034170) matrix metallopeptidase 14 (membrane-inserted)
  • domestic cat(101089776) matrix metallopeptidase 14 (membrane-inserted)
  • chicken(426253) matrix metallopeptidase 14 (membrane-inserted)

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-MT1-MMP Antibody, hinge region, from rabbit, purified by affinity chromatography,
종별 반응성
human, rat
응용분야
immunohistochemistry
western blot
Anti-MMP-14 Antibody, catalytic domain, clone 114-6G6, clone 114-6G6, Chemicon®, from mouse,
종별 반응성
human
응용분야
ELISA
immunohistochemistry

western blot
Anti-MMP-14 Antibody, serum, Chemicon®,
종별 반응성
human
응용분야
ELISA
flow cytometry

immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-MMP-14 Antibody, catalytic domain, clone LEM-2/63.1, clone LEM-2/63.1, Chemicon®, from mouse,
종별 반응성
mouse
응용분야
ELISA
immunoprecipitation (IP)

western blot
Anti-MMP-14 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
PD166793 hydrate, ≥98% (HPLC),
human, rat, mouse
Marimastat, ≥98% (HPLC),
human, rat, mouse

Proteins

제품 번호
설명
MMP-14, human, prodomain, catalytic domain, and hemopexin domain, E. coli recombinant, ,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human MMP14,
human
MISSION® esiRNA, targeting mouse Mmp14,
mouse