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Merck

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

동의어:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
종:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), cow MTOR (100139219), Horse MTOR (100051341), Goat MTOR (100860902), dog MTOR (478232), sheep MTOR (100271659), domestic guinea pig Mtor (100724938), chicken MTOR (419455) ...더
UniProtKB ID:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
Clone ID:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
SAB4301415
Anti-phospho-mTOR (pThr2446) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
SAB5701741
Anti-Phospho-mTOR-S2448 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
western blot
09-213
Anti-phospho-mTOR (Ser2448) Antibody, Upstate®, from rabbit,
종별 반응성
human
응용분야
western blot
SAB5700327
Anti-Phospho-mTOR-S2448 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
western blot
SAB2702296
Monoclonal Anti-mTOR antibody produced in mouse, clone GT649, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
immunohistochemistry
western blot

Small Molecule - Inhibitor

제품 번호
설명
종
SML0120
Perhexiline maleate salt, ≥98% (HPLC),
종
human

Proteins

제품 번호
설명
종
14-770-M
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
종
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
종
human

esiRNA

제품 번호
설명
종
EHU101641
MISSION® esiRNA, targeting human MTOR,
종
human