콘텐츠로 건너뛰기
Merck

SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

동의어:
PAI, PAI-1, PAI1, PLANH1
:
UniProtKB ID:
Clone ID:
  • Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
  • Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Custom & Knockdown Gene Products

ELISA

제품 번호
설명
Rhesus Macaque PAI-1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-SerPINE1 (AB1) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, human, mouse, pig, rabbit, rat, sheep
응용분야
immunohistochemistry
western blot
Anti-SERPINE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-SERPINE1 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
western blot
Anti-PAI-1/Serpin E1 Antibody, clone 6L6Y7, Rabbit Monoclonal, ,
종별 반응성
human
응용분야
western blot
Anti-PAI-1 (Ab-1) Mouse mAb (2), lyophilized, clone 2, Calbiochem®,
종별 반응성
human
응용분야

Proteins

제품 번호
설명
Plasminogen activator inhibitor 1 (PAI-1) human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SERPINE1,
human
MISSION® esiRNA, targeting mouse Serpine1,
mouse