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Merck

STAT5A

signal transducer and activator of transcription 5A

동의어:
MGF, STAT5
:
UniProtKB ID:
Clone ID:
  • Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
  • Mouse(20850) signal transducer and activator of transcription 5A
  • Rat(24918) signal transducer and activator of transcription 5A
  • dog(490968) signal transducer and activator of transcription 5A
  • naked mole-rat(101723770) signal transducer and activator of transcription 5A
  • domestic cat(101090913) signal transducer and activator of transcription 5A
  • domestic guinea pig(100716811) signal transducer and activator of transcription 5A
  • cow(282375) signal transducer and activator of transcription 5A
  • Horse(100052904) signal transducer and activator of transcription 5A
  • sheep(443419) signal transducer and activator of transcription 5A

Custom & Knockdown Gene Products

ELISA

제품 번호
설명
Phosphotyrosine STAT5A / Signal Transducer and Activator of Transcription 5A ELISA Kit, ,
human
Cell-Based ELISA for detecting phospho-STAT5 (pTyr694) in cultured cell lines, 96 assays,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho-STAT5A (pTyr694) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-STAT5A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
western blot
Anti-Phospho-STAT5A-Y694 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-Phospho-STAT5A-Y694 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2, clone 8-5-2, Upstate®, from mouse,
종별 반응성
bovine, human, mouse, rat, sheep
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human STAT5A,
human
MISSION® esiRNA, targeting mouse Stat5a,
mouse