Mucin from bovine submaxillary glands, item M3895, can be dissolved/reconstituted in H2O or dilute aqueous alkaline buffers.
M3895
Mucin from bovine submaxillary glands
Type I-S
동의어(들):
MUC
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제품정보 (DICE 배송 시 비용 별도)
Form:
powder
Biological source:
bovine submaxillary glands
다음으로 건너뛰기
biological source
bovine submaxillary glands
type
Type I-S
form
powder
composition
Bound sialic acids, 9-24%
technique(s)
electrophoresis: suitable
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
cow ... BSM(286841)
1 of 4
이 품목 | M1778 | A7517 | G3643 |
|---|---|---|---|
| biological source bovine submaxillary glands | biological source Porcine stomach | biological source bovine | biological source bovine plasma |
| technique(s) electrophoresis: suitable | technique(s) microbiological culture: suitable | technique(s) electrophoresis: suitable | technique(s) electrophoresis: suitable, mass spectrometry (MS): suitable |
| form powder | form partially purified powder | form lyophilized powder | form powder |
| Gene Information cow ... BSM(286841) | Gene Information - | Gene Information bovine ... ALB(280717) | Gene Information bovine ... ORM1(497200) |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. | UniProt accession no. |
General description
Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes.[1] It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain.[2] The sialic acid contributes to 30% of the molecular weight of mucin.[2] The central domain has many tandem repeats.[1]
Neuraminidase substrate.
Application
Mucin from bovine submaxillary glands has been used:
- in the quantification of mucin[3]
- as a component of artificial tear solution[4]
- as a substrate for recombinant sialidase Gardnerella vaginalis[5]
- to investigate a galactose-specific lectin from the red marine alga Ptilota filicina
- to study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa)
Biochem/physiol Actions
Albuminoid substance in mucus which gives it its ropy consistency
Other Notes
Similar to M 4503, but produced by Sigma.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Sasi B Yarragudi et al.
Carbohydrate polymers, 163, 216-226 (2017-03-08)
Targeted delivery and retention of drug formulations in the olfactory mucosa, the target site for nose-to-brain drug absorption is a major challenge due to the geometrical complexity of the nose and nasal clearance. Recent modelling data indicates that 10μm-sized microparticles
Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium
Brookes DM, et al.
British Journal of Pharmacology, 175(12), 2520-2534 (2018)
The central domain of bovine submaxillary mucin consists of over 50 tandem repeats of 329 amino acids: Chromosomal localization of the BSM1 gene and relations to ovine and porcine counterparts
Jiang W, et al.
European Journal of Biochemistry, 267(8), 2208-2217 (2000)
Proteolytic degradation of bovine submaxillary mucin (BSM) and its impact on adsorption and lubrication at a hydrophobic surface
Madsen JB, et al.
Langmuir, 31(30), 8303-8309 (2015)
Instability and breakup of model tear films
Bhamla MS, et al.
Investigative Ophthalmology & Visual Science, 57(3), 949-958 (2016)
문서
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
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