Skip to Content
Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Synonyms:
C-Kit, CD117, PBT, SCFR
Species:
Human KIT (3815), Mouse Kit (16590), Rat Kit (64030), Domestic Rabbit KIT (100327263), dog KIT (403811), domestic cat KIT (493766), Horse KIT (100009704), cow KIT (280832), Goat KIT (100861386), sheep KIT (780504) ...More
UniProtKB ID:
P10721, B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99
Gene ID:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB0992
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Species
human
RAB0731
Human KIT / Mast/Stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MABF360
Anti-CD117 (c-kit) Antibody (mouse), APC, clone ACK2, clone ACK2, 0.2 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
MABF361
Anti-CD117 (c-kit) Antibody (mouse), PE, clone ACK2, clone ACK2, 0.2 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunocytochemistry
immunohistochemistry
MABF149D
Anti-CD117 (c-Kit) (mouse), PE-Cy7, clone ACK2 Antibody, clone ACK2, from rat, PE-Cy7,
Species Reactivity
mouse
Application
flow cytometry
MABF511
Anti-CD117 (c-Kit) Antibody (mouse), PE, clone ACK2, clone ACK2, 0.2 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunocytochemistry
immunohistochemistry
WH0003815M2
Monoclonal Anti-KIT antibody produced in mouse, clone 6F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
CDS022173
Imatinib, ,
Species
human
PZ0012
Sunitinib malate, ≥98% (HPLC),
Species
human
CDS023580
Pazopanib, ,
Species
human
CDS023389
Dasatinib, ,
Species
human
SML2589
Dasatinib, ≥98% (HPLC),
Species
human

Proteins

Product Number
Description
Species
14-611-M
c-Kit (D816V) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant human c-Kit, amino acids 544-end containing the D816V mutation, for use in Kinase Assays.,
Species
human
SRP5310
c-KIT (Y823D), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
SRP5309
c-KIT (T670I), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
SRP5308
c-KIT (T670E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
SRP5299
c-KIT (D820E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
EHU000841
MISSION® esiRNA, targeting human KIT,
Species
human
EMU049661
MISSION® esiRNA, targeting mouse Kit,
Species
mouse