- Synthesis and antifungal activity of furo[2,3-f]quinolin-5-ols.
Synthesis and antifungal activity of furo[2,3-f]quinolin-5-ols.
Bioorganic & medicinal chemistry letters (2011-01-11)
Chung-Kyu Ryu, Yang Hui Kim, Ji-Hee Nho, Jung An Hong, Joo Hee Yoon, Aram Kim
PMID21215618
ABSTRACT
Furo[2,3-f]quinolin-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida,Aspergillus species, and Cryptococcus neoformans. Among them tested, many furo[2,3-f]quinolin-5-ols showed good antifungal activity. The results suggest that furo[2,3-f]quinolin-5-ols would be promising antifungal agents.
MATERIALS