Skip to Content
Merck
  • Phosphazene base-promoted halogen-zinc exchange reaction of aryl iodides using diethylzinc.

Phosphazene base-promoted halogen-zinc exchange reaction of aryl iodides using diethylzinc.

Chemical communications (Cambridge, England) (2006-08-22)
Masahiro Ueno, Andrew E H Wheatley, Yoshinori Kondo
ABSTRACT

The use of catalytic t-Bu-P4 base dramatically improved the performance of halogen-zinc exchange of aryl iodides, and the arylzinc derivatives were functionalized under copper-free reaction conditions.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Diethylzinc solution, 15 wt. % in toluene
Sigma-Aldrich
Diethylzinc solution, 1.0 M in heptane
Sigma-Aldrich
Diethylzinc solution, 1.0 M in hexanes
Sigma-Aldrich
Diethylzinc, ≥52 wt. % Zn basis