[Skip to Content](https://www.sigmaaldrich.com#main-content) [](https://www.sigmaaldrich.com/LT/en) Products Cart0 LTEN Products ProductsApplicationsServicesResourcesSupport [Login / Register](https://www.sigmaaldrich.com/oidc-sign-in) [Home](https://www.sigmaaldrich.com/)[Solid Phase Microextraction (SPME)](https://www.sigmaaldrich.com/applications/analytical-chemistry/sample-preparation/solid-phase-microextraction)Getting Started with SPME # Getting Started with SPME [Learn More About SPME](https://www.sigmaaldrich.com/applications/analytical-chemistry/sample-preparation/solid-phase-microextraction) SPME is inexpensive and reusable. The SPME process requires an SPME fiber assembly, holder, and a 0.75 mm ID SPME inlet liner. There are three types of SPME holders: manual holder for SPME method development, automated holders are available for a variety of autosamplers, and the portable field sampler is used for offsite or remote sampling. A starter pack of three different SPME fibers is recommended to evaluate the proper fiber for your sample. The starter pack contains both polar and non-polar coated fibers, as indicated by hub color. To optimize the GC analysis, use a .75mm ID SPME inlet liner and the Merlin Microseal, shown in the foreground, to replace the septum in the injection port. Different size vials are available that match the vial puck that comes with the sampling stand. The SPME sampling stand is ideal for proper support of the SPME holder and the stirring hotplate for control of temperature and agitation of the sample. __Related Articles__ - [Biodiesel](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/gas-chromatography/biodiesel) - [Automated Solid Phase Microextraction (SPME) Sampling](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/automated-spme-sampling) - [Bioanalysis with SPME](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/bioanalysis-with-spme) - [BioSPME for Plasma Protein Binding Assay: Details of Method Development and Optimization](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/biospme-plasma-protein-binding-assay) - [Solid Phase Microextraction: Frequently Asked Questions](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/faq) - [GC/MS/MS Analysis of BPA in Energy Drink](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/gc-ms-ms-analysis-of-bisphenol-a-bpa-in-a-fruit-flavored-energy-drink-cla010218a) - [Rugged SPME Sampling](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/nitinol-core-spme-fibers) - [SPME Fiber Performance Tips for Volatiles & Semi-Volatiles](https://www.sigmaaldrich.com/LT/en/technical-documents/technical-article/analytical-chemistry/solid-phase-microextraction/performance-tips) - [View More](https://www.sigmaaldrich.com/LT/en/search/facet-search?focus=sitecontent&term=facet-search) Top __Sign In To Continue__ To continue reading please sign in or create an account. 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