918962

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)

PEG average M_n 5000, PDLA average M_n 50000

• Synonym(s): Biodegradable, Block copolymer, Drug delivery, PEG-PLA, PLLA, mPEG-PLA, mPEG-PLLA
• Linear Formula: HO[CH(CH₃)COO]_m[CH₂CH₂O]_nCH₃

Properties

• form: solid
• Quality Level: 100
• mol wt: PDLA average M_n 50,000 (by NMR); PDLA average M_n 50000; PEG average M_n 5,000 (by NMR); PEG average M_n 5000
• color: white to yellow
• storage temp.: 2-8°C

Description

Application

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide) is an amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3