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922749

Poly(2-methacryloyloxyethyl phosphorylcholine)

Mn 9000

Synonym(s):

PMPC

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1 g
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MXP 5,030.00

About This Item

Linear Formula:
(C11H22NO6P)n
UNSPSC Code:
41116105
NACRES:
NA.23
Form:
powder or crystals

MXP 5,030.00


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form

powder or crystals

Quality Level

mol wt

Mn 9000

color

white to beige

SMILES string

O=C(OCCOP(OCC[N+](C)(C)C)([O-])=O)C(C)(C)CC

InChI

1S/C13H28NO6P/c1-7-13(2,3)12(15)18-10-11-20-21(16,17)19-9-8-14(4,5)6/h7-11H2,1-6H3

InChI key

SHNPVFQVGKUZPI-UHFFFAOYSA-N

Application

Poly (2-Methacryloyloxyethyl phosphorylcholine) (PMPC) is a methacrylate based polymer with a zwitterionic phosphorylcholine moiety on the side chain. The phosphorylcholine moiety is very similar to the head group of phospholipids in cell membranes. Due to this unique structure, PMPC showed excellent resistance to nonspecific protein adsorption, cell adhesion, and blood coagulation, as well as cell membrane penetration and underwater lubrication. PMPC has been widely exploited in a diverse range of applications, such as antifouling materials for water treatment, bioengineering, and nanomedicine.

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This Item
M6546730114925632
Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

form

powder or crystals

form

solid

form

powder or crystals

form

powder

color

white to beige

color

-

color

-

color

white

mol wt

Mn 9000

mol wt

-

mol wt

-

mol wt

PEG Mn 3000-7000


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Critical update on 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer science
T Goda, et al.
Journal of Applied Polymer Science, 132, 41766-41766 (2015)
Andrew Lewis et al.
Bioconjugate chemistry, 19(11), 2144-2155 (2008-11-01)
The water-soluble, biocompatible polymer poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) was evaluated for protein conjugation. PMPC is a zwitterionic polymer that is able to form a more compact conformation in aqueous solution than poly(ethylene glycol) (PEG). While a terminally functionalized N-hydroxysuccinimide derivative of



Global Trade Item Number

SKUGTIN
922749-1G04065266877984

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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