Merck

1.37117

SAFC

Dimethyl sulfoxide

EMPROVE® EXPERT, Ph. Eur., ChP, USP

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Synonym(s):
Methanesulfinylmethane, Methyl sulfoxide, Dimethyl(oxido)sulfur, DMSO, DMSO
Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
MDL number:
EC Index Number:
200-664-3

Agency

ChP
Ph. Eur.
USP

Quality Level

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

product line

EMPROVE® EXPERT

Assay

≥99.9% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

API processing | polymorph screening: suitable

refractive index

n20/D 1.479 (lit.)

kinematic viscosity

2.14 cSt

bp

189 °C (lit.)

mp

16-19 °C (lit.)

transition temp

flash point 87 °C

density

1.10 g/mL (lit.)

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation

storage temp.

2-30°C

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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1 of 4

This Item
D20500001211006RTC000103
Dimethyl sulfoxide EMPROVE® EXPERT, Ph. Eur., ChP, USP

1.37117

Dimethyl sulfoxide

Dimethyl sulfoxide European Pharmacopoeia (EP) Reference Standard

D2050000

Dimethyl sulfoxide

Dimethyl sulfoxide United States Pharmacopeia (USP) Reference Standard

1211006

Dimethyl sulfoxide

Dimethyl Sulfoxide Pharmaceutical Secondary Standard; Certified Reference Material

RTC000103

Dimethyl Sulfoxide

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

Quality Level

500

Quality Level

-

Quality Level

-

Quality Level

300

technique(s)

API processing | polymorph screening: suitable

technique(s)

-

technique(s)

-

technique(s)

-

form

liquid

form

-

form

-

form

-

transition temp

flash point 87 °C

transition temp

-

transition temp

-

transition temp

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Dimethyl sulfoxide is used as penetration enhancer in topical formulation, as cryopreservative in cell therapy and solvent in antibody drug conjugate production.
Due to its low microbial and endotoxin limits, Dimethyl Sulfoxide Emprove® Expert is especially suitable for high-risk applications.

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Specifications

8.0 g/m3 (20 °C)

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup


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Articles

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