Merck
All Photos(2)

648310-M

Millipore

Tris Base, Molecular Biology Grade - CAS 77-86-1 - Calbiochem

TRIS base is useful in the pH range of 7.0-9.0. Has a pKa of 8.1 at 25°C.

Synonym(s):
Tris base, Trometamol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris(hydroxymethyl)aminomethane, tris(Hydroxymethyl)aminomethane
Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
Beilstein:
741883
MDL number:

Quality Level

assay

≥99% (perchloric acid titration)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

solubility

water: 500 mg/mL

cation traces

heavy metals: ≤0.0005%

absorption

≤0.02 at 280 nm
≤0.03 at 260 nm

foreign activity

RNases, DNases, proteases, none detected

storage temp.

10-30°C

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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General description

Widely used as a biological buffer (absorbance: ≤0.03 at 260 nm; ≤0.02 at 280 nm). Useful in the pH range of 7.0-9.0. Has a pKa of 8.1 at 25°C.
Useful in the pH range of 7.0-9.0. Has a pKa of 8.1 at 25°C.

Warning

Toxicity: Irritant (B)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Quality

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