Merck
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91827

Supelco

Biotin

certified reference material, TraceCERT®

Synonym(s):
Bios II, Vitamin H, Vitamin B7, D-Biotin, Coenzyme R
Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein:
86838
EC Number:
MDL number:
eCl@ss:
34058011
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
TraceCERT®

product line

TraceCERT®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

mp

231-233 °C (lit.)

application(s)

clinical testing
pharmaceutical (small molecule)

format

neat

storage temp.

20-25°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Biotin is a bicyclic compound, which is widely distributed in food stuffs. It is essentially required as an important nutrient for animals.
Biotin is a water soluble vitamin, which functions as a coenzyme in several carboxylase-mediated metabolic reactions such as gluconeogenesis, biosynthesis of fatty acids, and metabolism of amino acids.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biotin may be used as a certified reference material for the quantification of the analyte in food samples, feed, tablets and premixes using high-performance liquid chromatography/avidin binding and high-performance liquid chromatography with tandem mass spectrometry.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

Nutrient Requirements of Dogs and Cats (2006)
Quantification of biotin in feed, food, tablets, and premixes using HPLC?MS/MS
Holler U, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 831(1-2), 8-16 (2006)
Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding
Staggs GC, et al.
J. Food Compos. Anal., 17(6), 767-776 (2004)
Sung Jae Shin et al.
Clinical and vaccine immunology : CVI, 15(8), 1277-1281 (2008-06-14)
We previously reported that protein antigens of serodiagnostic potential were more abundant in culture filtrates than cellular extracts from liquid cultures of Mycobacterium avium subsp. paratuberculosis (D. Cho and M. T. Collins, Clin. Vaccine Immunol. 13:1155-1161, 2006). Based on this
Juha A E Määttä et al.
BMC structural biology, 9, 63-63 (2009-10-01)
Avidins are proteins with extraordinarily high ligand-binding affinity, a property which is used in a wide array of life science applications. Even though useful for biotechnology and nanotechnology, the biological function of avidins is not fully understood. Here we structurally

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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