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L-Arginine monohydrochloride

reagent grade, ≥98% (HPLC), powder

(S)-(+)-Arginine hydrochloride, (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride
Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


reagent grade


≥98% (HPLC)




cell analysis: suitable




>235 °C


H2O: 50 mg/mL

SMILES string




InChI key


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L-Arginine monohydrochloride has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster. It has also been used to develop a non-invasive chronic pancreatitis model of rat.


25 kg in poly drum
1 kg in poly bottle
10, 25, 100, 500 g in poly bottle

Biochem/physiol Actions

L-Arginine is a semi-essential amino acid. This dibasic amino acid acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.
Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Are solutions of Product No. A5131 (L-Arginine monohydrochloride) autoclavable?

    Arginine is routinely autoclaved as a component of microbial media with no adverse effects; therefore solutions of A5131 L-Arginine monohydrochloride may be autoclaved.

  6. What is the method of preparation process for the A5131 L-Arginine monohydrochloride?

    No animal proteins or products are used in the fermentation process or purification of the L-Arginine.

  7. What are the solubility properties of L-Arginine monohydrochloride (Product No. A5131)?

    L-Arginine monohydrochloride is soluble in water at a concentration of 1M (210 mg/mL).

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Severe Chronic Pancreatitis due to Recurrent Acute Injury: Non-Invasive Chronic Pancreatitis Model of Rat
Surendra Sharma
Pancreas (2016)
Yang Liu et al.
Biochemical and biophysical research communications, 525(3), 620-625 (2020-03-03)
The circadian clock, a biochemical oscillator, plays a fundamental role in health and diseases. Ferroptosis, a type of regulated cell death driven by oxidative stress, is a prominent feature in iron-induced tissue injury. However, whether an impaired circadian clock contributes...
J. P. Felix D'Mello
Amino Acids in Human Nutrition and Health (2012)
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature (2017)

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