Merck
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A5882

Supelco

Antipyrine

analytical standard

Synonym(s):
2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one, Phenazone
Empirical Formula (Hill Notation):
C11H12N2O
CAS Number:
Molecular Weight:
188.23
Beilstein:
157775
EC Number:
MDL number:
PubChem Substance ID:

grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

109-111 °C (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChI key

VEQOALNAAJBPNY-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742)

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Antipyrine may be used as:
  • Pharmaceutical reference standard for the determination of the analyte in animal plasma and serum by various chromatography techniques.
  • Internal standard for the analysis of creatinine and uric acid in human plasma by micellar electrokinetic chromatography.
  • Reference standard to investigate the effect of diseases, pharmaceuticals, and environmental factors on hepatic oxidative metabolism activity in humans and animals in vivo, owing to its physicochemical, biochemical, and pharmacokinetic properties.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

25, 100, 500 g in poly bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Antipyrine, indocyanine green, and lorazepam determined in plasma by high-pressure liquid chromatography.
Awni WM and Bakker LJ
Clinical Chemistry, 35(10), 2124-2126 (1989)
Serum antipyrine concentrations determined by micellar electrokinetic capillary chromatography
Brunner LJ, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 622(1), 98-102 (1993)
Simultaneous determination of creatinine and uric acid in human plasma and urine by micellar electrokinetic chromatography
Miyake M, et al.
Journal of High Resolution Chromatography, 14(3), 181-185 (1991)
Qureshi, M.
Mikrochimica Acta, 831-831 (1970)
Weiss, K.G. and Boltz, D.F.
Analytica Chimica Acta, 55, 77-77 (1971)

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