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P8155

Sigma-Aldrich

(R)-(−)-Phenylephrine hydrochloride

analytical standard

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Synonym(s):
(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
Linear Formula:
HOC6H4CH(CH2NHCH3)OH·HCl
CAS Number:
Molecular Weight:
203.67
Beilstein:
4158948
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

grade

analytical standard

Quality Level

form

powder

packaging

vial of 250 mg

mp

143-145 °C (lit.)

SMILES string

OC1=CC([C@H](CNC)O)=CC=C1.Cl

InChI

1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key

OCYSGIYOVXAGKQ-FVGYRXGTSA-N

Gene Information

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This Item
P6126PHR1017BP284
Phenylephrine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

PHR1017

Phenylephrine Hydrochloride

Phenylephrine hydrochloride British Pharmacopoeia (BP) Reference Standard

BP284

Phenylephrine hydrochloride

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

-

grade

analytical standard

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

packaging

vial of 250 mg

packaging

-

packaging

-

packaging

-

mp

143-145 °C (lit.)

mp

143-145 °C (lit.)

mp

143-145 °C (lit.)

mp

143-145 °C (lit.)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Biochem/physiol Actions

α-Adrenergic agonist

Packaging

Supplied in amber screw-cap vials

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Dale A Currigan et al.
Anesthesiology, 121(5), 930-936 (2014-09-10)
Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right
C A Boly et al.
British journal of anaesthesia, 111(5), 750-758 (2013-07-11)
Left-ventricular end-systolic elastance (Ees) is an index of cardiac contractility, but the invasive nature of its assessment has limited perioperative application. We explored the feasibility of a minimally invasive method of Ees estimation for perioperative assessment of cardiac function and
Doreen Schmidl et al.
Investigative ophthalmology & visual science, 54(3), 1964-1970 (2013-02-27)
We determined whether administration of a nitric oxide synthase (NOS) inhibitor alters optic nerve head blood flow (ONHBF) regulation during isometric exercise in healthy subjects. Our study was done in a randomized, placebo-controlled, double-masked, three-way crossover design. A total of
P F Soeding et al.
British journal of anaesthesia, 111(2), 229-234 (2013-03-23)
The upright sitting or beachchair position is associated with hypotension, risk of cerebral hypoperfusion, and cerebral injury. We hypothesized that by increasing arterial pressure with phenylephrine administration, cerebral perfusion, and postoperative recovery would be improved. Thirty-four patients undergoing elective shoulder
Stephanie W Watts et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(6), 1320-1328 (2013-04-06)
Obesity and hypertension are comorbid in epidemic proportion, yet their biological connection is largely a mystery. The peptide chemerin is a candidate for connecting fat deposits around the blood vessel (perivascular adipose tissue) to arterial contraction. We presently tested the

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