Merck
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PHR1001

Supelco

Sucrose

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
α-D-Glc-(1→2)-β-D-Fru, α-D-Glucopyranosyl β-D-fructofuranoside, β-D-Fructofuranosyl-α-D-glucopyranoside, D(+)-Saccharose, Sugar
Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein:
90825
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to BP 818
traceable to Ph. Eur. S1600000
traceable to USP 1623637

API family

sucrose

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

185-187 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

CZMRCDWAGMRECN-UGDNZRGBSA-N

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This Item
S18881623637S1174
Sucrose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1001

Sucrose

-
Sucrose BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99.5% (GC)

Sigma-Aldrich

S1888

Sucrose

Essential+ Grade
Sucrose United States Pharmacopeia (USP) Reference Standard

USP

1623637

Sucrose

-
Sucrose analytical standard, for enzymatic assay kit SCA20

Supelco

S1174

Sucrose

-
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

environmental
food and beverages

format

neat

format

-

format

neat

format

neat

storage temp.

2-30°C

storage temp.

room temp

storage temp.

-

storage temp.

-

Quality Level

300

Quality Level

300

Quality Level

-

Quality Level

100

General description

Sucrose is a disaccharide and a naturally occurring carbohydrate found in plants. It is available as a component of food and is widely used as an additive in food, confectionery, beverages and therapeutically in sugar pastes commonly used to promote wound healing. Sucrose is widely used in oral pharmaceutical formulations. In the powdered form, it serves as a dry binder or as a bulking agent and sweetener in chewable tablets and lozenges.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7831 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Sucrose meets USP testing specifications

Sigma-Aldrich

S3929

Sucrose

Sucrose British Pharmacopoeia (BP) Reference Standard

BP818

Sucrose

Sucrose puriss., meets analytical specification of Ph. Eur., BP, NF

Sigma-Aldrich

16104

Sucrose

Sucrose ≥99.5%

Sigma-Aldrich

S8501

Sucrose

Sucrose ACS reagent

Sigma-Aldrich

S5016

Sucrose

1,4-Benzoquinone United States Pharmacopeia (USP) Reference Standard

USP

1056504

1,4-Benzoquinone

Sucrose ≥99.5% (GC)

Sigma-Aldrich

S9378

Sucrose

Evaluation of the Health Aspects of Sucrose as a Food Ingredient, 69 (1976)
Handbook of Pharmaceutical Excipients, 69(6) (2009)
Julia B Cordero et al.
The EMBO journal, 33(13), 1474-1491 (2014-05-03)
The non-receptor tyrosine kinase c-Src, hereafter referred to as Src, is overexpressed or activated in multiple human malignancies. There has been much speculation about the functional role of Src in colorectal cancer (CRC), with Src amplification and potential activating mutations
Denise Harrison et al.
Pediatrics, 130(5), 918-925 (2012-10-10)
The use of oral sucrose has been the most extensively studied pain intervention in newborn care to date. More than 150 published studies relating to sweet-taste-induced calming and analgesia in human infants have been identified, of which 100 (65%) include
Rafaela Ribeiro Reis et al.
Plant science : an international journal of experimental plant biology, 221-222, 59-68 (2014-03-25)
Drought is one of the most challenging agricultural issues limiting sustainable sugarcane production and, in some cases, yield losses caused by drought are nearly 50%. DREB proteins play vital regulatory roles in abiotic stress responses in plants. The transcription factor

Articles

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