Dextran

Name: Dextran
Brand: SIGMA

enzymatic synth.

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About This Item

Linear Formula:

[C₆H₁₀O₅]_n

CAS Number:

9004-54-0

EC Number:

232-677-5

MDL number:

MFCD00130935

UNSPSC Code:

12352201

NACRES:

NA.25

Key Documents

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form

powder

mol wt

M_r ~1,500

color

colorless to almost colorless

solubility

water: 1.5 g/10 mL, clear

storage temp.

room temp

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

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This Item	00892	00271	00270
Sigma-Aldrich 31394 Dextran	Supelco 00892 Dextran	Supelco 00271 Dextran	Supelco 00270 Dextran
solubility water: 1.5 g/10 mL, clear	solubility -	solubility -	solubility -
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
form powder	form powder or crystals	form powder or crystals	form powder or crystals
storage temp. room temp	storage temp. -	storage temp. -	storage temp. -
color colorless to almost colorless	color -	color -	color -
mol wt M_r ~1,500	mol wt M_n ~55,500, M_p ~66,700, M_w ~80,900	mol wt M_n ~18,300, M_p ~21,400, M_w ~23,800	mol wt M_n ~8,110, M_p ~9,890, M_w ~11,600

Application

Dextran is a branched glucan composed of linear α(1→6) linked glucose units and α (1→3) link initiated branches. Dextran ranges in size from 10,000 to 150,000 Kd. Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Dextran and protamine-based solid lipid nanoparticles as potential vectors for the treatment of X-linked juvenile retinoschisis.

Diego Delgado et al.

Human gene therapy, 23(4), 345-355 (2012-02-03)

The goal of the present study was to analyze the potential application of nonviral vectors based on solid lipid nanoparticles (SLN) for the treatment of ocular diseases by gene therapy, specifically X-linked juvenile retinoschisis (XLRS). Vectors were prepared with SLN

Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance.

Dmitri Simberg et al.

Biomaterials, 30(23-24), 3926-3933 (2009-04-28)

In order to understand the role of plasma proteins in the rapid liver clearance of dextran-coated superparamagnetic iron oxide (SPIO) in vivo, we analyzed the full repertoire of SPIO-binding blood proteins using novel two-dimensional differential mass spectrometry approach. The identified

Comparison of contrast media and low-molecular-weight dextran for frequency-domain optical coherence tomography.

Yuichi Ozaki et al.

Circulation journal : official journal of the Japanese Circulation Society, 76(4), 922-927 (2012-02-04)

Although an intracoronary frequency-domain optical coherence tomography (FD-OCT) system overcomes several limitations of the time-domain OCT (TD-OCT) system, the former requires injection of contrast media for image acquisition. The increased total amount of contrast media for FD-OCT image acquisition may

Molecular Weight Effects on the Miscibility Behavior of Dextran and Maltodextrin with Poly(vinylpyrrolidone).

Van Eerdenbrugh B, Taylor LS.

Pharmaceut. Res., doi: 10-doi: 10 (2012)

Protective effect of dextrans on glucose oxidase denaturation and inactivation.

Melda Altikatoglu et al.

Artificial cells, blood substitutes, and immobilization biotechnology, 40(4), 261-265 (2012-01-28)

In the present study, the stabilizing effect of dextrans as additives on the denaturation and inactivation of glucose oxidase (GOD) was investigated. Three different molecular weighted dextrans (M(w) 17.5, 75, 188 kD) were used with different concentrations. Dramatically increased enzyme

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