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5133

Sigma-Aldrich

FibriCol®

Collagen solution from Bovine hide, 97% Type I with the remainder of Type III collagen, suitable for cell culture

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NACRES:
NA.75

biological source

(Collagen solution from Bovine hide)

Quality Level

sterility

sterile-filtered

Assay

>99% (SDS-PAGE Electrophoresis – Silver Stain, SDS-PAGE)

form

solution

packaging

pkg of 20 mL

technique(s)

cell culture | mammalian: suitable

solubility

water: miscible

shipped in

wet ice

storage temp.

2-8°C

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C4243C21245074
Sigma-Aldrich

Sigma-Aldrich

5133

FibriCol®

sterility

sterile-filtered

sterility

sterile-filtered

sterility

sterile-filtered

sterility

sterile

assay

>99% (SDS-PAGE Electrophoresis – Silver Stain, SDS-PAGE)

assay

≥99.9% (SDS-PAGE)

assay

-

assay

≥99% (SDS-PAGE Electrophoresis – Silver Stain, SDS-PAGE)

form

solution

form

liquid

form

liquid

form

solid

packaging

pkg of 20 mL

packaging

pkg of 100 mL, pkg of 20 mL

packaging

pkg of 50 mL

packaging

pkg of 35 mL

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

General description

FibriCol® collagen is approximately 97% Type I collagen with the remainder being comprised of Type III collagen. It contains a high monomer content as measured by gel permeation chromatography.

It is ideal for applications where high concentrations of collagen are needed. FibriCol® collagen is provided in a 20 mL volume and is contained in user-friendly packaging for use and storage. FibriCol® is sterile filtered and is supplied as a ready to use solution.

Application

FibriCol® has been used:

  • in the preparation of liposome-loaded co-gels to treat methicillin-resistant Staphylococcus aureus (MRSA) infections in vitro and in vivo
  • in the preparation of gelatin-methacrylate (gelMA)-collagen gels to study the effects of stiffness and fiber density on cellular behavior in breast cancer cell lines
  • in the preparation of collagen hydrogels to study its effects on macrophage response in partial thickness abdominal wall defect rat models

Legal Information

FibriCol is a registered trademark of Advanced BioMatrix, Inc.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Host macrophage response to injectable hydrogels derived from ECM and ?-helical peptides
Nazia M, et al.
Acta Biomaterialia, 111, 141-152 (2020)
Anthony J Berger et al.
Biomaterials, 141, 125-135 (2017-07-07)
The extracellular microenvironment provides critical cues that guide tissue development, homeostasis, and pathology. Deciphering the individual roles of these cues in tissue function necessitates the development of physically tunable culture platforms, but current approaches to create such materials have produced
Raj Kumar Thapa et al.
Acta biomaterialia, 103, 115-128 (2019-12-18)
Wound infections are a significant clinical problem affecting millions of people worldwide. Topically applied antibacterial formulations with longer residence time and controlled antimicrobial release would offer significant benefits for improved prevention and treatment of infected wounds. In this study, we

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