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5138

Sigma-Aldrich

SphereCol®

Human Collagen Coated Beads

NACRES:
NA.75

biological source

human

sterility

irradiated

form

liquid

packaging

pkg of 10 g

application(s)

cell culture | mammalian: suitable

bead size

~125-212 μm

surface area

360 cm2/g

storage temp.

room temp

General description

SphereCol® human Type I collagen coated beads are ideal for growing cell in suspension. The collagen coated beads provide a natural in vivo-like environment to promote high cell growth while providing a large surface area for cells to attach with optimal surface area to volume ratios. SphereCol® provides a 3D bio-scaffold which is optimal in many cell culture procedures.

SphereCol®, human collagen coated beads are coated with highly purified Type I human collagen derived from a human fibroblast cell culture process, VitroCol. The collagen provides an optimal coating on the beads to enhance cell attachment, cell viability, cell proliferation and cell function. The collagen beads range in size from about 125 to 212 micron.

Application

SphereCol®, human collagen coated beads provide a surface area of 360cm2/gram of beads.

Legal Information

SphereCol is a registered trademark of Advanced BioMatrix, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

Romel Dator et al.
Chemical research in toxicology, 33(8), 2087-2098 (2020-04-16)
African American (AA) smokers are at a higher risk of developing lung cancer compared to whites. The variations in the metabolism of nicotine and tobacco-derived carcinogens in these groups were reported previously with the levels of nicotine metabolites and carcinogen-derived...
Liu Ying et al.
International journal of biological sciences, 16(12), 2180-2191 (2020-06-19)
The histone H3K9 methyltransferase SETDB2 is involved in cell cycle dysregulation in acute leukemia and has oncogenic roles in gastric cancer. In our study, we found that SETDB2 plays essential roles in breast cancer stem cell maintenance. Depleted SETDB2 significantly...
Zhenzhen Meng et al.
Journal of cellular physiology, 235(2), 932-943 (2019-06-27)
Histone demethylase KDM7A regulates neuronal differentiation and development in mammals. In this study, we found that KDM7A was also required for breast cancer stem cells (BCSCs) maintenance. Silencing KDM7A significantly reduced the BCSCs population and mamosphere formation in vitro, and...
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Songjie Cai et al.
Scientific reports, 10(1), 14249-14249 (2020-08-30)
Solid organ transplantation is a lifesaving therapy for patients with end-organ disease. Current immunosuppression protocols are not designed to target antigen-specific alloimmunity and are uncapable of preventing chronic allograft injury. As myeloid-derived suppressor cells (MDSCs) are potent immunoregulatory cells, we...

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