88440

Poly(ethylene glycol)

BioUltra, 200

• Synonym(s): PEG
• Linear Formula: H(OCH₂CH₂)_nOH
• CAS Number: 25322-68-3
• MDL number: MFCD00081839
• PubChem Substance ID: 24889096
• NACRES: NA.26

Properties

• Quality Level: 100
• product line: BioUltra
• form: liquid
• mol wt: M_r 190-210
• impurities: insoluble matter:, passes filter test; ≤0.02% peroxides (as H₂O₂):
• refractive index: n20/D 1.460
• pH: 5.5-7.0 (25 °C, 50 mg/mL in H₂O)
• solubility: H₂O: 50 mg/mL at 25 °C, clear, colorless
• density: 1.124 g/mL at 20 °C
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤500 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 50 mg/mL in H₂O
• UV absorption: λ: 260 nm A_max: 0.06; λ: 280 nm A_max: 0.03
• SMILES string: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion.

Application

Poly(ethylene glycol) (PEG) has been used to determine the signaling role of NADPH oxidase 4 (Nox4) in the modulation of vascular endothelial growth factor (VEGF) expression. In the species-specific quantitative polymerase chain reaction (qPCR) to dilute lysates.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 519.8 °F - closed cup
• Flash Point(C): 271.00 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves