Merck
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90190

Sigma-Aldrich

Transferrin from human blood plasma

≥95% (GE)

Synonym(s):
Human transferrin, Siderophilin
CAS Number:
EC Number:
MDL number:
NACRES:
NA.61

Quality Level

biological source

human plasma

assay

≥95% (GE)

form

powder or crystals

mol wt

Mr ~79550

technique(s)

tissue culture: suitable

impurities

≤0.01% iron traces (AAS)

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow or pink

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... TF(7018)

Application

Transferrin is an important supplement in serum-free tissue culture media.

Biochem/physiol Actions

Transferrin is glycoprotein, approx. 80 kDa, with two binding sites for iron. It transports iron from its primary store in the liver to tissues that require iron, primarily bone marrow and spleen, but also brain. It binds Fe3+ extremely tightly (Kdiss 10-30 to 10-27), protecting against oxidant effects of free plasma iron.

Other Notes

Review: Iron transport and storage

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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