A0278

L-Ascorbic acid

reagent grade

• Synonym(s): L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
• Empirical Formula (Hill Notation): C₆H₈O₆
• CAS Number: 50-81-7
• Molecular Weight: 176.12
• Beilstein: 84272
• EC Number: 200-066-2
• MDL number: MFCD00064328
• UNSPSC Code: 12352209
• PubChem Substance ID: 24890417
• NACRES: NA.26

Properties

• biological source: synthetic
• grade: reagent grade
• Assay: ≥98% (with Iodine, titration)
• form: powder
• technique(s): HPLC: suitable
• color: white to light yellow
• pH: 1.0-2.5 (25 °C, 176 g/L in water)
• mp: 190-194 °C (dec.)
• solubility: water: soluble 50 mg/mL
• SMILES string: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• InChI key: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
• Gene Information: human ... SLC23A2(9962)

Description

General description

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates.[1] It is a water-soluble vitamin.[2]

Application

L-Ascorbic acid has been used as a standard in high performance liquid chromatography (HPLC) for quantification of L-ascorbic acid.[3]

L-Ascorbic acid may be used as standard in assay for erythrocyte hemolysis mediated by peroxyl free radicals.[4] It may be used for the reduction of graphene oxide sheets.[5]

Biochem/physiol Actions

L-Ascorbic acid is an anti-oxidant. L-Ascorbic acid (vitamin C) is important for many enzymatic reactions for maintaining prosthetic metal ions in their reduced forms (for example, Fe²⁺, Cu⁺). It protects tissues from oxidative damage by scavenging free radicals.[6] It has mild reductive ability and nontoxic property. It is commonly employed reductant in the laboratory.[5] Colorimetric determination of ascorbic acid in plasma using acid phosphotungstate has been reported.[7]

L-ascorbic acid modified poly(ester urethane)s might facilitate soft tissue regeneration.[8] It also helps in increasing iron absorption by tissues. In addition, it aids in tyrosine metabolism and microsomal drug metabolism.[1]

Caution

May darken in storage.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves