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A2218

Sigma-Aldrich

L-Ascorbic acid

meets USP testing specifications

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Synonym(s):
L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

Agency

USP/NF
meets USP testing specifications

Assay

99.0-100.5%

form

solid

technique(s)

cell culture | mammalian: suitable

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

application(s)

pharmaceutical (small molecule)

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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1 of 4

This Item
A596095212A92902
L-Ascorbic acid meets USP testing specifications

Sigma-Aldrich

A2218

L-Ascorbic acid

-
L-Ascorbic acid BioXtra, ≥99.0%, crystalline

Sigma-Aldrich

A5960

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Premium Grade
L-Ascorbic acid tested according to Ph. Eur.

Sigma-Aldrich

95212

L-Ascorbic acid

-
L-Ascorbic acid 99%

Sigma-Aldrich

A92902

L-Ascorbic acid

-
assay

99.0-100.5%

assay

≥99.0%

assay

99.0-100.5%

assay

99%

form

solid

form

crystalline

form

solid

form

powder

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

solubility

H2O: 0.5 M, clear, colorless

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

General description

L-ascorbic acid (AA) is a naturally occurring C vitamer. It is soluble in water. It is present in fruits and vegetables.

Application

L-ascorbic acid has been used as a supplement in DMEM/F12/ osteoblast induction medium. It has also been used as a component in liquid Ham′s isolation media.

Biochem/physiol Actions

L-ascorbic acid (AA) can block and treat scurvy. It possesses antioxidant properties. In the fermentation of wine, AA acid serve as a food additive and antioxidant.
Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Compositional analysis of foods
Liquid Chromatography (2013)
Biological characteristics of muscle-derived satellite cells isolated from rats at different postnatal days
Yu R, et al.
Cytotechnology, 67(3), 397-408 (2015)
Analysis of vitamins by liquid chromatography
Liquid Chromatography, 571-615 (2017)
1, 3, 2-Dioxathiolane oxides: epoxide equivalents and versatile synthons
Lohray BB and Bhushan V
Advances in Heterocyclic Chemistry, 68, 90-181 (1997)
An improved protocol for the isolation and cultivation of embryonic mouse myocytes
Rodgers LS, et al.
Cytotechnology, 59(2), 93-102 (2009)

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