cell culture | mammalian: suitable
white to off-white
106-108 °C (lit.)
H2O: 100 mg/mL (with heating)
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Eye Irrit. 2
13 - Non Combustible Solids
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
The pH of a 1% solution is 2.0-2.8. You may need to adjust the pH of the media with NaOH. Or, prior to addition to the media, you can initially dilute the NAC with PBS, and then add it to the culture media.
Aqueous solutions of cysteine oxidize to cystine on contact with air at neutral or alkaline pH. We recommend making aqueous solutions fresh. NAC is relatively stable in acid. Solutions in acid are stable and can be stored at -20 °C.
Cell culture testing is performed at 0.82 g/L. The exact concentration will depend upon your application.
We have not tested the half-life of NAC solutions in our labs here at Sigma. However, this subject has been reviewed in Neuropsychopharmacology, 29, 2018-2023 (2004).
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.
Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.