Merck
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C3355

Sigma-Aldrich

Coelenterazine hcp

solid

Synonym(s):
CLZN-hcp
Empirical Formula (Hill Notation):
C25H25N3O2
CAS Number:
Molecular Weight:
399.48
MDL number:
PubChem Substance ID:
NACRES:
NA.83

assay

≥95% (HPLC)

Quality Level

form

solid

solubility

methanol: 1 mg/mL, clear, yellow to orange

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)C2=CN3C(=O)C(Cc4ccccc4)=NC3=C(CC5CCCC5)N2

InChI

1S/C25H25N3O2/c29-20-12-10-19(11-13-20)23-16-28-24(21(26-23)14-17-8-4-5-9-17)27-22(25(28)30)15-18-6-2-1-3-7-18/h1-3,6-7,10-13,16-17,26,29H,4-5,8-9,14-15H2

InChI key

YEGCUOQUFAXCMK-UHFFFAOYSA-N

General description

Coelenterazine hcp is a semisynthetic analog of coelenterazine.[1]

Application

Coelenterazine hcp has been used:
  • as a component of coelenterazine reagent in the reporter assay[2]
  • in the purification of Renilla luciferase-labeled Annexin V[3]
  • in evaluating the activity of aequorin in Escherichia coli[4]

Biochem/physiol Actions

Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine[5] and a faster response time than native coelenterazine.[4]

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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