Risk Alleles in CFH and ARMS2 Are Independently Associated with Systemic Complement Activation in Age-related Macular Degeneration.
Smailhodzic D., et al.
P J Francis et al.
Journal of medical genetics, 46(5), 300-307 (2008-11-19)
Age related macular degeneration (AMD) is a leading cause of blindness. AMD is a complex disorder caused by genetic and environmental factors in which single nucleotide polymorphisms (SNPs) in the genes CFH and LOC387715/HTRA1/ARMS2 have prognostic importance for progression to...
Jordan E Inglis et al.
Advances in physiology education, 32(4), 317-321 (2008-12-03)
The immune system is a vital physiological component that affords animals protection from disease and is composed of innate and adaptive mechanisms that rely on cellular and dissolved components. The serum complement system is a series of dissolved proteins that...