216 °C (dec.) (lit.)
water: 50.0-52.0 mg/mL, clear, orange to red
DNA synthesis | interferes
human ... TOP2A(7153)
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Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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Doxorubicin has excitation maximum at 470 nm and an emission maximum at 585 nm in ethanol.
Product No. D1317, Doxorubicin hydrochloride solution has been discontinued and is no longer available. We now offer Product No. D1515 which is a powder.
Aqueous solutions are unchanged after one month at 5 °C but unstable at higher temperatures or at either acid or alkaline pH. Several studies cite that stability is related to pH, exposure to light and the medium used for storage. Doxorubicin hydrochloride is subject to light degradation at <0.5 mg/mL, with considerable loss of bioactivity. If stored at 25 °C in the dark in 5% glucose, pH 4.7 (or 3.3% glucose + 0.3% sodium chloride, pH 4.4), solutions were stable (5% or less change) for at least 4 weeks.
The solubility of doxorubicin is tested in water (50 mg/mL), yielding a clear orange to red solution.
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