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D4876

Dextran from Leuconostoc mesenteroides

average mol wt 150,000

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D4876-50G

MXP 2,490.00

D4876-100G

MXP 4,251.00

D4876-500G

MXP 17,617.00

D4876-1KG

MXP 30,301.00

MXP 2,490.00

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About This Item

Linear Formula:
(C6H10O5)n
CAS Number:
9004-54-0
EC Number:
232-677-5
MDL number:
MFCD00130935
UNSPSC Code:
12352201
NACRES:
NA.25

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biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

200

form

powder

optical activity

[α]/D 199°

mol wt

average mol wt 150,000

color

white

solubility

H2O: soluble 20 mg/mL

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

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Show Differences

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This Item
D3759D8821D1662
Dextran from Leuconostoc mesenteroides average mol wt 150,000

Sigma-Aldrich

D4876

Dextran from Leuconostoc mesenteroides

Dextran from Leuconostoc mesenteroides average mol wt 48,000-90,000

Sigma-Aldrich

D3759

Dextran from Leuconostoc mesenteroides

Dextran from Leuconostoc mesenteroides average mol wt 60,000-76,000

Sigma-Aldrich

D8821

Dextran from Leuconostoc mesenteroides

Dextran from Leuconostoc mesenteroides average mol wt 35,000-45,000

Sigma-Aldrich

D1662

Dextran from Leuconostoc mesenteroides

biological source

bacterial (Leuconostoc mesenteroides)

biological source

bacterial (Leuconostoc mesenteroides)

biological source

bacterial (Leuconostoc mesenteroides)

biological source

bacterial (Leuconostoc mesenteroides)

solubility

H2O: soluble 20 mg/mL

solubility

H2O: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

water: 100 mg/mL at 25 °C, colorless to faintly yellow

solubility

H2O: 100 mg/mL, clear, colorless

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

color

white

color

white

color

white to off-white

color

white

optical activity

[α]/D 199°

optical activity

[α]/D 199°

optical activity

[α]20/D 190 to 201 °, c = 2% (w/v) in water

optical activity

[α]/D 199°

Application

Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants and physical structure components.[1] Dextrans may be used as long hydrophilic spacer arms to improve the performance (freedom of movement) of conjugated/bound proteins. Dextrans may be derivatized for use in biosensor systems.[2] Dextran 150 may be used to study iron delivery to cells, cell membrane permeabilization and red blood cell aggregation.
Use of dextrans as long and hydrophilic spacer arms improves the performance of immobilized proteins acting on macromolecules.

Preparation Note

With the exception of the highest MW dextran, D5501 (MW range = 5 million to 40 million), dextrans are very water soluble. Sigma tests the solubility of dextrans at concentrations generally exceeding 30 mg/ml in water. Dextrans are also freely soluble in DMSO, formamide, ethylene glycol, and glycerol. Neutral-aqueous dextran solutions can be sterilized by autoclaving at 110-115oC for 30 to 45 minutes. Dextran can be hydrolyzed by strong acids at high temperatures. The terminal reducing end group of dextran can be oxidized in alkaline solutions.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000507676
0000507675
0000507674
0000507674
0000507675

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Mengyun Lia et al.
Archives of animal nutrition, 65(6), 477-485 (2012-01-20)
Iron (Fe) is an essential and important trace element for animals. In order to study its metabolism and relationship with hepcidin, piglet models of Fe-deficiency and Fe-overload were established by intramuscular injection with different doses of Fe-dextran (150 mg Fe/ml)
Scott A Myers et al.
Experimental neurology, 256, 25-38 (2014-04-03)
CD36 is a pleiotropic receptor involved in several pathophysiological conditions, including cerebral ischemia, neurovascular dysfunction and atherosclerosis, and recent reports implicate its involvement in the endoplasmic reticulum stress response (ERSR). We hypothesized that CD36 signaling contributes to the inflammation and
Hideto Katsuta et al.
Investigative ophthalmology & visual science, 54(6), 4102-4108 (2013-05-23)
To elucidate the role of signals mediated by EphB4 receptor tyrosine kinase and its transmembrane ephrinB2 ligand in corneal lymphatic capillaries. To detect expression of ephrinB2 and EphB4 in mouse corneas, immunohistochemistry of flat-mount corneas from 6- to 10-week-old wild-type
Yang Yang et al.
Biochimica et biophysica acta, 1840(1), 288-293 (2013-10-01)
Abnormal adhesion of red blood cells (RBCs) to vascular endothelium is often associated with reduced levels of sialic acids on RBC membranes and with elevated levels of pro-adhesive plasma proteins. However, the synergistic effects of these two factors on the
Elizabeth M Bradshaw et al.
Nature neuroscience, 16(7), 848-850 (2013-05-28)
In our functional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) risk allele was associated with greater cell surface expression of CD33 in the monocytes (t50 = 10.06, P(joint) = 1.3 × 10(-13)) of young
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