G7384

Gallic acid

97.5-102.5% (titration)

• Synonym(s): 3,4,5-Trihydroxybenzoic acid
• Linear Formula: (HO)₃C₆H₂CO₂H
• CAS Number: 149-91-7
• Molecular Weight: 170.12
• Beilstein: 2050274
• EC Number: 205-749-9
• MDL number: MFCD00002510
• PubChem Substance ID: 24895304
• NACRES: NA.25

Properties

• Quality Level: 200
• Assay: 97.5-102.5% (titration)
• mp: 251 °C (dec.) (lit.)
• SMILES string: OC(=O)c1cc(O)c(O)c(O)c1
• InChI: 1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
• InChI key: LNTHITQWFMADLM-UHFFFAOYSA-N

Description

General description

Gallic acid is a natural product produced during the hydrolysis of tannins. It elicits anti-inflammatory, antifungal, and antimicrobial properties. Gallic acid is an important chemical used in the food and pharmaceutical industry. It also exhibits gastroprotective, cardioprotective, neuroprotective, and metabolic disease prevention properties.

Application

Gallic acid has been used:

• as a standard for the quantification of extractable phenolics by external calibration
• as a standard to determine the total tannin content of oak root powder using the Folin-Ciocalteu method
• as a phenolic acid to study it′s in vitro antiviral, antibacterial, cytotoxicity and antifungal activities

Biochem/physiol Actions

Gallic acid is a water soluble phenolic acid present in grapes and in the leaves of many plants. Gallic acid esters, such as tannins, catechin gallates and aliphatic gallates are potent antioxidants in vitro. However, gallic acid itself also appears to have antioxidant, anticarcinogenic and antiangiogenic activity in vitro.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves