All Photos(2)

H2270

Sigma-Aldrich

Hydrocortisone 21-hemisuccinate sodium salt

powder, BioReagent, suitable for cell culture

Synonym(s):
11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate sodium salt, Cortisol 21-hemisuccinate sodium salt
Empirical Formula (Hill Notation):
C25H33NaO8
CAS Number:
Molecular Weight:
484.51
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

biological source

synthetic (organic)

product line

BioReagent

assay

≥90% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC([O-])=O)=O)=O)=C1.[Na+]

InChI

1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1

InChI key

HHZQLQREDATOBM-CODXZCKSSA-M

Gene Information

human ... NR3C1(2908)

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General description

Hydrocortisone for use in epithelial and endothelial adherent cell culture applications.

Packaging

100 mg in poly bottle

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Ying Yuan et al.
Clinical epigenetics, 12(1), 135-135 (2020-09-08)
Hepatitis B virus covalently closed circular DNA (HBV cccDNA) is assembled by histones and non-histones into a chromatin-like cccDNA minichromosome in the nucleus. The cellular histone acetyltransferase GCN5, displaying succinyltransferase activity, is recruited onto cccDNA to modulate HBV transcription in
Takahiro Michiba et al.
Auris, nasus, larynx, 40(2), 162-166 (2012-07-31)
Some patients with sudden sensorineural hearing loss (SSNHL) are frustrated by residual tinnitus even after accomplishment of the treatment for SSNHL. In the present prospective study, we examined patients' backgrounds of sex, laterality and age together with changes in hearing
Crenguta Livia Calma et al.
Tropical doctor, 42(1), 54-55 (2011-11-08)
This case report focuses on hydatidosis, one of the most important parasitic zoonoses in Romania. We describe an interesting paediatric case of an eight-year old boy from a rural region presenting with a both giant and life-threatening pulmonary cyst (that
Kelsey A Hart et al.
American journal of veterinary research, 73(1), 68-75 (2011-12-30)
To compare daily endogenous cortisol production rate and the pharmacokinetics of an i.v. bolus of hydrocortisone between neonatal foals and adult horses. 10 healthy full-term 2- to 4-day-old foals and 7 healthy adult horses. Blood samples were collected from each
Naked & unconscious: crew's misdiagnosis could have cost patient her life.
Kimberly Doran
JEMS : a journal of emergency medical services, 37(10), 28-28 (2013-01-25)

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