H8502

Dopamine hydrochloride

• Synonym(s): 2-(3,4-Dihydroxyphenyl)ethylamine hydrochloride, 3,4-Dihydroxyphenethylamine hydrochloride, 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride, 3-Hydroxytyramine hydrochloride
• Linear Formula: (HO)₂C₆H₃CH₂CH₂NH₂·HCl
• CAS Number: 62-31-7
• Molecular Weight: 189.64
• Beilstein: 3656720
• EC Number: 200-527-8
• MDL number: MFCD00012898
• PubChem Substance ID: 24277897
• NACRES: NA.77

Properties

• form: powder
• Quality Level: 200
• color: light tan
• mp: 248-250 °C (lit.)
• solubility: alcohol: 20 mg/mL; H₂O: soluble
• storage temp.: 2-8°C
• SMILES string: Cl[H].NCCc1ccc(O)c(O)c1
• InChI: 1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
• InChI key: CTENFNNZBMHDDG-UHFFFAOYSA-N
• Gene Information: human ... ADRB1(153)

Description

General description

Dopamine (DA) works as neurotransmitter in the central nervous system. It is a catecholamine made from the amino acid L-tyrosine. It also works as a hormone in vesicles of the adrenal medulla, thereby controlling heart beat rate and blood pressure. Absence of DA-containing neurons is associated with parkinson′s disease.

Application

• Dopamine hydrochloride has been used to study dopamine-mediated transient modulation of the physiological responses in whiteleg shrimp, Litopenaeus vannamei.
• It has been used to study dopamine-mediated changes in immunity susceptibility to Lactococcus garvieae in the freshwater giant prawn, Macrobrachium rosenbergii.
• It has been used to study the molecular link between dopamine-induced oxidative stress and mHtt (mutant Huntingtin) toxicity in relation to the activation of the autophagy pathway in an ‘in vitro′ model of parkinsonian Huntington′s Disease.

Packaging

5, 10, 25, 100 g in poly bottle

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Caution

Light sensitive

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H8502.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves