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N4912

Sigma-Aldrich

NMA-Gly-Cys-Gly-Val-Leu-Leu-Lys(dnp)-Arg-Arg-NH2 trifluoroacetate salt

≥95% (HPLC), solid

All Photos(1)
Synonym(s):
NMA-GCGVLLK(dnp)RR-NH2
Empirical Formula (Hill Notation):
C56H90N20O14S · xC2HF3O2
Molecular Weight:
1299.50 (free base basis)
MDL number:
MFCD08277027
NACRES:
NA.77

Quality Level

100

Assay

≥95% (HPLC)

form

solid

storage condition

desiccated
protect from light
under inert gas

color

yellow

solubility

H2O: ≥0.5 mg/mL

shipped in

wet ice

storage temp.

−20°C

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Sigma-Aldrich

Sigma-Aldrich

N4912

NMA-Gly-Cys-Gly-Val-Leu-Leu-Lys(dnp)-Arg-Arg-NH2 trifluoroacetate salt

Sigma-Aldrich

Sigma-Aldrich

89064

4-Phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-D-Arg trifluoroacetate salt

Ala-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt ≥98% (HPLC), lyophilized powder

Sigma-Aldrich

A3227

Ala-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt

Mca-YVADAPK(Dnp)-OH trifluoroacetate ≥97% (HPLC)

Sigma-Aldrich

SML2944

Mca-YVADAPK(Dnp)-OH trifluoroacetate

form

solid

form

powder

form

lyophilized powder

form

film or powder

storage condition

desiccated, protect from light, under inert gas

storage condition

-

storage condition

-

storage condition

-

color

yellow

color

-

color

white

color

white to dark beige

solubility

H2O: ≥0.5 mg/mL

solubility

-

solubility

H2O: >10 mg/mL

solubility

-

shipped in

wet ice

shipped in

-

shipped in

-

shipped in

-

Amino Acid Sequence

Nme-Asp-Gly-Cys-Gly-Val-Leu-Leu-Lys-DNP-Arg-Arg-NH2

Biochem/physiol Actions

Notch 1 Peptide, fluorogenic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yoshihito Taniguchi et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(6), 4014-4019 (2002-03-14)
Notch receptors undergo three distinct proteolytic cleavages during maturation and activation. The third cleavage occurs within the plasma membrane and results in the release and translocation of the intracellular domain into the nucleus to execute Notch signaling. This so-called gamma-secretase

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