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P4957

Sigma-Aldrich

Poly-L-ornithine solution

mol wt 30,000-70,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture

CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

Quality Level

sterility

sterile-filtered

product line

BioReagent

form

solution

mol wt

30,000-70,000

packaging

pkg of 50 mL

concentration

0.01%

application(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

shipped in

ambient

storage temp.

2-8°C

SMILES string

Br.NCCCC(N)C(O)=O

Related Categories

General description

Poly-L-ornithine is a positively charged synthetic amino acid polymer.

Application

Poly-L-ornithine has been used successfully for the attachement and study of neural cell differentiation and outgrowth. Recommended as a cell culture substratum when using 0.5 ml of a 0.1 mg/ml solution to coat 25 cm2.
Poly-L-ornithine solution has been used in the induction of differentiation.

Biochem/physiol Actions

Poly-L-ornithine helps to improve the penetration of substances into cells. It can induce the uptake of DNA.

Preparation Note

Prepared in cell culture grade water.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Ewoud B Compeer et al.
Nature communications, 9(1), 1597-1597 (2018-04-25)
Endocytosis of surface receptors and their polarized recycling back to the plasma membrane are central to many cellular processes, such as cell migration, cytokinesis, basolateral polarity of epithelial cells and T cell activation. Little is known about the mechanisms that...
Plant Protoplasts: International Review of Cytology (2013)
Interferon (2009)
Ocular Neuroprotection (2003)
Areechun Sotthibundhu et al.
EXCLI journal, 15, 829-841 (2017-03-10)
Melatonin, secreted mainly by the pineal gland, plays roles in various physiological functions including protecting cell death. We showed in previous study that the proliferation and differentiation of precursor cells from the adult mouse subventricular zone (SVZ) can be modulated...

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