Merck
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P9625

Sigma-Aldrich

Phenazine methosulfate

≥90% (UV)

Synonym(s):
PMS, N-Methylphenazonium methyl sulfate, 5-Methylphenazinium methyl sulfate
Linear Formula:
C13H11N2 · CH3SO4
CAS Number:
Molecular Weight:
306.34
Beilstein:
3898869
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥90% (UV)

form

powder

mp

158-160 °C (dec.) (lit.)

λ

0.01 g/L in H2O, 1 cm path

UV absorption

λ: 387.5 nm Amax: ≥90%

antibiotic activity spectrum

fungi

Mode of action

DNA synthesis | interferes
cell membrane | interferes

storage temp.

−20°C

SMILES string

COS([O-])(=O)=O.C[n+]1c2ccccc2nc3ccccc13

InChI

1S/C13H11N2.CH4O4S/c1-15-12-8-4-2-6-10(12)14-11-7-3-5-9-13(11)15;1-5-6(2,3)4/h2-9H,1H3;1H3,(H,2,3,4)/q+1;/p-1

InChI key

RXGJTUSBYWCRBK-UHFFFAOYSA-M

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General description

Phenazines are heterocyclic compounds produced as secondary metabolites by bacteria.

Application

Phenazine methosulfate is used with ascorbic acid to determine nitric oxide reductase activity.
Phenazine methosulfate has been used:
  • as a component of succinate dehydrogenase enzyme substrate solution
  • to induce superoxide radical generation in red blood cell suspensions and to study its influence on RBC deformability
  • as a component of complex II histochemistry media

Packaging

500 mg in glass bottle
1, 5, 10, 25 g in glass bottle

Biochem/physiol Actions

Phenazine m ethosulfate (PMS) acts as a good electron acceptor. PMS is reduced non-enzymatically by (nicotinamide adenine dinucleotide) NADH and (nicotinamide adenine dinucleotide phosphate) NADPH.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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