S1764

Sigma-Aldrich

Complement sera human

lyophilized powder

MDL number:
NACRES:
NA.61

Quality Level

biological source

human

form

lyophilized powder

origin

USA origin

application(s)

cell culture | mammalian: suitable

impurities

virus, tested

shipped in

dry ice

storage temp.

−20°C

Related Categories

Application

The activity of complement sera can be determined by hemolytic assays in vitro.

Physical form

Lyophilized powder from indicated amount of serum

Analysis Note

Hemolytic titer (CH50 units per ml) is determined by method of Kabat and Mayer. Actual titer given on label.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

Savannah E Butler et al.
Frontiers in immunology, 11, 618685-618685 (2021-02-16)
Understanding humoral immune responses to SARS-CoV-2 infection will play a critical role in the development of vaccines and antibody-based interventions. We report systemic and mucosal antibody responses in convalescent individuals who experienced varying severity of disease. Whereas assessment of neutralization...
Helen Kotanides et al.
Cancer immunology research, 8(10), 1300-1310 (2020-09-03)
The programmed cell death protein 1 receptor (PD-1) and programmed death ligand 1 (PD-L1) coinhibitory pathway suppresses T-cell-mediated immunity. We hypothesized that cotargeting of PD-1 and PD-L1 with a bispecific antibody molecule could provide an alternative therapeutic approach, with enhanced...
So Hee Dho et al.
Scientific reports, 8(1), 8960-8960 (2018-06-14)
Decay-accelerating factor (CD55 or DAF) inhibits complement-dependent cytotoxicity. We determined that CD55 is overexpressed in 76.47% of human non-small cell lung cancer tissue specimens. We therefore developed a lutetium-177-labeled chimeric monoclonal antibody against CD55. CD55-specific single-chain variable fragment (scFv) was...
Chiaki Kawabata et al.
Biological & pharmaceutical bulletin, 44(2), 219-224 (2021-02-02)
Baculovirus vectors (BVs) are safely able to transduce foreign genes and express them in mammalian cells. However, the transduction activity of BVs is strongly reduced by the attack of serum complement, which is one of the major obstacles in the...
Jordan E Inglis et al.
Advances in physiology education, 32(4), 317-321 (2008-12-03)
The immune system is a vital physiological component that affords animals protection from disease and is composed of innate and adaptive mechanisms that rely on cellular and dissolved components. The serum complement system is a series of dissolved proteins that...

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