Live cell imaging in real time allows scientists to monitor dynamic cellular events that otherwise escape observation using traditional endpoint techniques like fixed imaging and PCR that capture only a static moment in time. Our portfolio of live cell imaging reagents includes novel fluorescent cell labeling technologies for cell tracking, fluorescent lentiviral biosensors, traditional fluorescent dyes and probes to analyze cellular events in real-time. These reagents are optimal for capturing dynamic cellular events with real-time incubation and imaging systems like the CellASIC® ONIX2 Microfluidic live cell imaging system.
PKH and CellVue® Fluorescent Cell Linker Kits provide fluorescent membrane labeling of live cells for long-term live cell imaging experiments.
Key attributes of PKH and CellVue® dyes include:
LentiBrite™ Fluorescent Lentiviral Biosensors are a suite of pre-packaged lentiviral particles that code for fluorescent proteins associated with autophagy, apoptosis, and cell structure for insights from these processes in live cells.
Lentiviral Biosensors feature:
BioTracker Live Cell dyes are cell-permeable dyes for live-cell applications such as organelle labeling, apoptosis detection, cell viability and cell health analysis, hypoxia monitoring, reactive oxygen species tracking, calcium indicator function, and neural and stem cell (SCR150, SCT029, SCT046) cultures.
BrightCell™ Photostable Media products are cell culture media and supplements that provide exceptional support for cell health during prolonged exposure to the high-energy light used for fluorescence microscopy. BrightCell™ media products also exhibit very low levels of autofluorescence and photobleaching, for dramatically better data quality from fluorescent live cell imaging.
LuminiCell Tracker™ fluorescent nanoparticles provide an effective, simple, and nontoxic reagent for long-term cell tracking experiments. Based on aggregation-induced emission (AIE) technology, these cell tracking dyes have been encapsulated into biocompatible, cell-permeable, fluorescent nanoparticles (AIE Dot) that provide enhanced photostability, ultra-bright fluorescence, and low cellular toxicity for bioimaging applications over extended periods of time.