Downstream Process & Formulation Chemicals

Emprove^® Chemicals Portfolio

• Emprove^® Evolve is for early stages of biopharmaceutical manufacturing, bridging the gap between lab-grade and GMP compliant raw and starting materials while providing transparent supply chain information and documentation.
• Emprove^® Essential is for moderate-risk applications, offering compliance to IPEC-PQG GMP Guide and/or EXCiPACT™ Certification Standard, as well as supply chain transparency and regulatory support designed to assist drug manufacturers’ formalized risk assessments.
• Emprove^® Expert is for higher-risk applications where the lowest microbiological and endotoxin levels are of utmost importance. Along with the risk management features of Emprove^® Essential, the Emprove^® Expert line yields products with specified low microbiological and endotoxin levels, supporting the overall risk mitigation strategy.
• For more information, visit our Emprove^® Chemicals page.

mAb Processing Applications

Our broad range of downstream chemicals and buffers helps to guide your monoclonal antibody from upstream processing to the final fill. You will find compounds that perform a variety of functions, including mAb modification and stabilization.

Plasma Processes

Increasing yields and maintaining safety are major challenges in plasma processes. Our downstream chemicals provide the tools you need to run complex plasma-fractionation processes successfully, by maintaining process safety.

Vaccines and Gene Therapy

Vaccine and gene therapy manufacturers need to reach high yields, maintain product safety, and accelerate development timelines. Our proven portfolio of reliable and consistent chemicals and manufacturing enzymes such as Benzonase^® endonuclease helps you cope with those challenges, supporting your vaccine and gene therapy processes from harvest throughout your entire downstream process.

Bacterial Fermentation Applications

Using microbial expression systems such as yeast and bacteria to manufacture simpler molecules offers reduced production cost and significantly higher upstream productivity. Our portfolio supports any step from the reactor to final product, including purification and modification.