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Haoqi Liu et al.
Nanoscale research letters, 10(1), 959-959 (2015-06-17)
Mesenchymal stem cells (MSCs) have been used for therapy of type 1 diabetes mellitus. However, the in vivo distribution and therapeutic effects of transplanted MSCs are not clarified well. Herein, we reported that CdSe/ZnS quantum dots-labeled MSCs were prepared for
Arshad Mehmood Abbasi et al.
International journal of molecular sciences, 16(6), 13507-13527 (2015-06-16)
Mango (Mangifera indica L.), also called "the king of fruits", is one of the most popular fruits in tropical regions. Pulp and peel samples of mango cultivars were analyzed to estimate total phenolic, total flavonoid and total anthocyanin contents. Phenolic
Masataka Hosoi et al.
Experimental hematology, 42(9), 816-825 (2014-05-27)
Induced pluripotent stem cells (iPS) derived from disease cells are expected to provide a new experimental material, especially for diseases from which samples are difficult to obtain. In this study, we generated iPS from samples from patients with primary and
Eunsu Chung et al.
Biosensors & bioelectronics, 64, 560-565 (2014-10-14)
Surface-enhanced Raman scattering (SERS)-based aptasensor platform, using double strand DNA-embedded Au/Ag core-shell nanoparticles, has been developed for the ultrasensitive detection of bisphenol A (BPA) in water. By combining optimally controlled Au/Ag core-shell nanoparticles with the selective BPA binding characteristics of
Kaoru Washio et al.
The International journal of oral & maxillofacial implants, 29(1), e117-e121 (2014-01-24)
The objective of this study was to establish a method for accurate cell counting from matrix-rich cell sheets in the clinical setting. Human periodontal ligament (HPDL) cells were obtained from healthy donors to prepare PDL cell sheets. To obtain single
F De Vadder et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(3), 443-448 (2015-01-15)
Intestinal gluconeogenesis (IGN) promotes metabolic benefits through activation of a gut-brain neural axis. However, the local mediator activating gluconeogenic genes in the enterocytes remains unknown. We show that (i) vasoactive intestinal peptide (VIP) signaling through VPAC1 receptor activates the intestinal
Karen Schimpf et al.
Journal of AOAC International, 96(4), 802-807 (2013-09-05)
This method for the determination of vitamin C by HPLC allows for the separation and quantitation of L-ascorbic acid in infant, pediatric, and adult nutritional products. Liquids, semisolids, and powders ranging from 2 to 1000 mg/kg in their consumable forms
Praveen K Mandapalli et al.
Drug delivery, 21(8), 605-614 (2013-12-18)
The objective of this study is to investigate the influence of charge of model small molecules on their encapsulation and release behavior in layer-by-layer microcapsules (LbL-MC). Poly(styrene sulfonate) and poly(ethylene imine) were sequentially adsorbed on calcium carbonate sacrificial templates to
Wenting Jia et al.
Neurobiology of aging, 36(2), 1183-1193 (2014-12-04)
Elevated iron levels and increased expression of divalent metal transporter 1 (DMT1) in the substantia nigra of Parkinson's disease (PD) have been reported. Nedd4 family-interacting protein 1 (Ndfip1), an adaptor protein for the Nedd4 family of ubiquitin ligases, played an
Hao Lin et al.
Drug design, development and therapy, 8, 973-982 (2014-07-30)
Apoptosis of osteoblasts triggered by high-dose glucocorticoids (GCs) has been identified as a major cause of osteoporosis. However, the underlying molecular mechanisms accounting for this action remain elusive, which has impeded the prevention and cure of this side effect. Sulforaphane
Mirosława Teleszko et al.
Journal of agricultural and food chemistry, 63(16), 4120-4129 (2015-04-22)
The aim of this study was to determine selected phytochemicals in berries of eight sea buckthorn (Hippophaë rhamnoides subsp. mongolica) cultivars, including lipophilic and hydrophilic compounds. In the experiment chromatographic analyses, GC (phytosterols and fatty acids), UPLC-PDA-FL, LC-MS (polyphenols), and
Yuval Silberman et al.
Alcoholism, clinical and experimental research, 39(11), 2154-2162 (2015-10-28)
Ethanol (EtOH) modulation of central amygdala (CeA) neurocircuitry plays a key role in the development of alcoholism via activation of the corticotropin-releasing factor (CRF) receptor (CRFR) system. Previous work has predominantly focused on EtOH × CRF interactions on the CeA GABA circuitry;
Sayeh Khanjani et al.
Journal of tissue engineering and regenerative medicine, 9(11), E124-E134 (2013-03-19)
In recent years, the advantages of menstrual blood-derived stem cells (MenSCs), such as minimal ethical considerations, easy access and high proliferative ability, have inspired scientists to investigate the potential of MenSCs in cell therapy of different diseases. In order to
M Veera Narayana Reddy et al.
European journal of medicinal chemistry, 45(5), 1828-1832 (2010-02-04)
Synthesis of 3,3'-(1,4-phenylene)-bis[2-alkoxycarbonyl-alkyl)-2-thio-benzoxaphos-phinines] (3a-j) were accomplished via two step process. It involves the prior preparation of monochloride intermediate (2) and its subsequent reaction with the amino acid esters in dry tetrahydrofuran-toluene in the presence of triethylamine at reflux temperature. These
Yuanshu Zhou et al.
Molecular bioSystems, 11(9), 2560-2567 (2015-07-28)
Flk-1 (VEGF receptor 2) is a well-defined mesodermal progenitor marker and the Flk-1-positive (Flk-1(+)) cells derived from embryonic stem cells (ESCs) have been known to generate hemangioblasts and cardiovascular progenitor cells, which are formed in the early and late stages
Zhimei Zhong et al.
European journal of medicinal chemistry, 43(10), 2171-2177 (2007-12-08)
Chitosan (CS) with two different molecular weights was modified by reacting with 4-hydroxyl-5-chloride-1,3-benzene-disulfo-chloride or 2-hydroxyl-5-chloride-1,3-benzene-disulfo-chloride to give new 2-(4(or 2)-hydroxyl-5-chloride-1,3-benzene-di-sulfanimide)-chitosan (2-HCBSAHCS, 2-HCBSALCS, 4-HCBSAHCS, 4-HCBSALCS). The structure of the derivatives was characterized by FT-IR and 13C NMR spectroscopy. The antioxidant activities
Xinjie Cai et al.
Journal of clinical periodontology, 42(4), 380-389 (2015-02-19)
The implantation of bone marrow-derived mesenchymal stem cells (MSCs) has previously been shown successful to achieve periodontal regeneration. However, the preferred pre-implantation differentiation strategy (e.g. maintenance of stemness, osteogenic or chondrogenic induction) to obtain optimal periodontal regeneration is still unknown.
D D Simon et al.
Cells, tissues, organs, 200(2), 104-117 (2015-05-01)
Cell-populated collagen gels have provided significant insight into the cellular contractile mechanisms and cell-matrix interactions that are necessary for compacting and remodeling extant matrix. Nevertheless, little research has been devoted towards determining how cells entrench these deformations that contribute to
Ilaria Colzi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 94, 411-418 (2015-06-29)
To date the effectiveness of antibiotics is undermined by microbial resistance, threatening public health worldwide. Enhancing the efficacy of the current antibiotic arsenal is an alternative strategy. The administration of antimicrobials encapsulated in nanocarriers, such as liposomes, is considered a
Aijun Wang et al.
Stem cells translational medicine, 4(6), 659-669 (2015-04-26)
Myelomeningocele (MMC)-commonly known as spina bifida-is a congenital birth defect that causes lifelong paralysis, incontinence, musculoskeletal deformities, and severe cognitive disabilities. The recent landmark Management of Myelomeningocele Study (MOMS) demonstrated for the first time in humans that in utero surgical
Tina P Dale et al.
PloS one, 10(7), e0133745-e0133745 (2015-07-22)
Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progressive cellular aging and
Jeong-Wook Oh et al.
Talanta, 147, 453-459 (2015-11-26)
Negatively charged multi-walled carbon nanotubes (MWCNTs) were prepared using simple sonication technique with non-toxic citric acid (CA) for the electrochemical detection of dopamine (DA). CA/MWCNTs were placed on glassy carbon (GC) electrodes by drop-casting method and then electrochemical determinations of
Clémentine Bosch-Bouju et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(48), 15836-15850 (2014-11-28)
Motor thalamus (Mthal) is a key node in the corticobasal ganglia (BG) loop that controls complex, cognitive aspects of movement. In Parkinson's disease (PD), profound alterations in neuronal activity occur in BG nuclei and cortex. Because Mthal is located between
Francisca Alcayaga-Miranda et al.
Stem cell research & therapy, 6, 32-32 (2015-04-19)
Stem cells isolated from menstrual fluid (MenSCs) exhibit mesenchymal stem cell (MSCs)-like properties including multi-lineage differentiation capacity. Besides, menstrual fluid has important advantages over other sources for the isolation of MSCs, including ease of access and repeated sampling in a
Jie Yu et al.
Theranostics, 5(9), 931-945 (2015-07-15)
The ability to selectively destroy cancer cells while sparing normal tissue is highly desirable during the cancer therapy. Here, magnetic targeted photothermal therapy was demonstrated by the integration of MoS2 (MS) flakes and Fe3O4 (IO) nanoparticles (NPs), where MoS2 converted
Afrouz Yousefi et al.
International journal of pharmaceutics, 472(1-2), 175-184 (2014-06-21)
Angiogenesis is one of the hallmarks of cancer which renders it an attractive target for therapy of malignancies. Tumor growth suppression can be achieved by inhibiting angiogenesis since it would deprive tumor cells of oxygen and vital nutrients. Activation of
Rebecca Josowitz et al.
PloS one, 9(7), e101316-e101316 (2014-07-11)
The use of human stem cell-derived cardiomyocytes to study atrial biology and disease has been restricted by the lack of a reliable method for stem cell-derived atrial cell labeling and purification. The goal of this study was to generate an
Koji Y Arai et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 22(6), 701-711 (2014-09-17)
Epidermal-dermal interaction plays important roles in physiological events such as wound healing. In this study, we examined a double paracrine mechanism between keratinocytes and fibroblasts through interleukin-1 (IL-1) and an IL-1-induced inflammatory mediator prostaglandin E₂ (PGE₂) using the skin equivalent.
G J Molderings et al.
Deutsche medizinische Wochenschrift (1946), 139(30), 1523-1534 (2014-05-08)
In the present paper clinical phenotypes, pathogenetic relationships, and diagnostic algorithms as well as therapeutic concepts of/for systemic mast cell activation disease are reviewed. The reader should be able to recognize and diagnose a systemic mast cell activation disease, as
Jay J Cao et al.
Calcified tissue international, 97(2), 145-155 (2015-04-24)
This study investigated whether exercise or antioxidant supplementation with vitamin C and E during exercise affects bone structure and markers of bone metabolism in obese rat. Sprague-Dawley rats, 6-week old, were fed a normal-fat diet (NF, 10 % kcal as
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